fMRI results.

<p>(A) Regions showing activity reductions [infrequently repeated (IR) > frequently repeated (FR) trials] to repeated simulations of the future included medial prefrontal cortex, posterior cingulate cortex, lateral temporal cortex (extending into lateral parietal cortex), thalamus, lateral prefrontal cortex, and cuneus. (B) Pulvinar nucleus (left) and orbitofrontal cortex (right) respectively showed selective reductions to repeated simulations of negative and positive future events. For illustrative purposes, bar graphs depict percent signal change for IR and FR negative, positive, and neutral trials. Error bars represent standard errors of the mean. (C) Regions showing activity increases to repeated simulations of the future (FR trials > IR trials) included bilateral ventral precuneus and bilateral inferior parietal lobule. All maps are shown as <i>p</i> < 0.001 (uncorrected) with minimum 10 voxels to help facilitate visualization.