<p>Sections of the eye from naive mice (A) as well as from EAU mice at 21 days after injection with hIRBP(1–20) and maintenance on a control (B), ω-6 LCPUFA (C), or ω-3 LCPUFA (D) diet were stained with hematoxylin-eosin. The histological score for EAU determined from the histological findings is indicated. GCL, ganglion cell layer; INL, inner nuclear layer; ONL, outer nuclear layer. Red arrowheads, inflammatory cells in the vitreous and retina; yellow arrows, retinal folds; red asterisks, granulomatous lesions.</p
<p>(A) Optic nerves were stained with luxol fast blue (LFB) and hematoxylin and eosin (HE) (upper tw...
<p>Immunofluorescence staining of DAPI (blue) oxLDL (red) and CD31 (green) using 12μm ocular section...
<p>EAU was induced in B10RIII mice by immunization with 8 ug IRBP in CFA. Cross (A) and horizontal (...
<p>Mice were anesthetized for examination with a digital medical scope at 14 days after induction of...
<p>Mouse eyes were taken from 18–24 months old mice and processed for H-E staining. A–C, representat...
<p>EAU was induced in B10RIII mice by immunization with 8 ug IRBP in CFA. <b>A</b>, Normal retinal l...
<p>(A) Representative retinal images of H&E-stained retinal section from age-matched normal uninject...
<p><b>A–D,</b> Mice were immunized with IRBP in adjuvant and eyes were collected at the indicated da...
<p>EAU was induced in B10RIII mice by immunization with 8 µg IRBP peptide in CFA. The kinetics of di...
<p><b>(A)</b> Positive staining was observed in the naïve retina, specifically in the outer plexifor...
<p>(A) EAU clinical score determined from fundus images obtained from mice at14 days after injection...
<p>Normal retina morphology was seen in WT mice (A), while the retina appeared disrupted in these mi...
<p>Sections of eyes of WT mice and deficient mice (12 weeks old; <i>n</i> = 3 per group) were staine...
<p>Retinal lesions were visualized using Micron-II fundus imaging and Bioptigen SD-OCT imaging syste...
A, A C57BL/6J mouse on P66. B, An RPE65−/− mouse on P95. C, A C57BL/6J mouse on P120. D, An RPE65−/−...
<p>(A) Optic nerves were stained with luxol fast blue (LFB) and hematoxylin and eosin (HE) (upper tw...
<p>Immunofluorescence staining of DAPI (blue) oxLDL (red) and CD31 (green) using 12μm ocular section...
<p>EAU was induced in B10RIII mice by immunization with 8 ug IRBP in CFA. Cross (A) and horizontal (...
<p>Mice were anesthetized for examination with a digital medical scope at 14 days after induction of...
<p>Mouse eyes were taken from 18–24 months old mice and processed for H-E staining. A–C, representat...
<p>EAU was induced in B10RIII mice by immunization with 8 ug IRBP in CFA. <b>A</b>, Normal retinal l...
<p>(A) Representative retinal images of H&E-stained retinal section from age-matched normal uninject...
<p><b>A–D,</b> Mice were immunized with IRBP in adjuvant and eyes were collected at the indicated da...
<p>EAU was induced in B10RIII mice by immunization with 8 µg IRBP peptide in CFA. The kinetics of di...
<p><b>(A)</b> Positive staining was observed in the naïve retina, specifically in the outer plexifor...
<p>(A) EAU clinical score determined from fundus images obtained from mice at14 days after injection...
<p>Normal retina morphology was seen in WT mice (A), while the retina appeared disrupted in these mi...
<p>Sections of eyes of WT mice and deficient mice (12 weeks old; <i>n</i> = 3 per group) were staine...
<p>Retinal lesions were visualized using Micron-II fundus imaging and Bioptigen SD-OCT imaging syste...
A, A C57BL/6J mouse on P66. B, An RPE65−/− mouse on P95. C, A C57BL/6J mouse on P120. D, An RPE65−/−...
<p>(A) Optic nerves were stained with luxol fast blue (LFB) and hematoxylin and eosin (HE) (upper tw...
<p>Immunofluorescence staining of DAPI (blue) oxLDL (red) and CD31 (green) using 12μm ocular section...
<p>EAU was induced in B10RIII mice by immunization with 8 ug IRBP in CFA. Cross (A) and horizontal (...