<p><b>A, B, and C</b>, representative microphotographs of brain slices from transgenic 5XFAD mice after immunochemical double-staining with monoclonal Anti-Human β Amyloid Protein antibody (Sigma, 1:300) and secondary antibody with fluorophore Alexa 594 (Invitrogen, 1:300) (red fluorescent dye), as well as monoclonal anti-C-terminal YB-1 fragment antibody (Sigma, Y0396, 1:1000) and secondary goat anti-rabbit antibody labeled with Alexa 488 (Life Technology A-11008, 1:1000) (green fluorescence).</p
Purpose. 18F-FC119S is a positron emission tomography (PET) tracer for imaging β-amyloid (Aβ) plaque...
<p>Immunohistochemical staining of β-amyloid plaques using A) anti-Aβ (1–42) polyclonal antibody B) ...
<p><b>A</b>) Western blot with the antibody M3.2 (specific for rodent β-amyloid) using hippocampal t...
<p>Abscissa, categorized groups of experimental animals. Ordinate, ELISA-estimated amount of mouse β...
<p><b>A</b>, Age-dependent decrease of percentage of plaque-free transgenic 5XFAD mice treated with ...
<p>Brain sections from mice injected with targeted liposomes (<b>A, D, G, J</b>) were probed with tw...
<p>The left column shows staining in the MEC region of MPS IIIB (−/−) mice, with the middle and righ...
<p><b>A.</b> Levels of Aβ in brain tissue were determined using monoclonal antibody 4G8 that recogni...
<p>Coronal brain sections from 22-week-old wild-type control littermates (A, C, E) and 5XFAD transge...
<p>YM3711 at a dose of 100 µg was injected weekly to 15-month old model mice for 6 weeks and the bra...
<p>(<b>A–C</b>) Representative half brain sections of WT mice, vehicle or SS-treated APP/PS1 mice st...
<p>Sections prepared from the hippocampus (A, D, G, J, K, M) and the cortex (B, E, H), of a 12 month...
<p><b>Abscissa</b>, age of mice (month); <b>ordinate</b>, plaque density (n/mm<sup>2</sup>) in view ...
<p>(A) Immunostaining of Aβ peptide (anti-Aβ 6E10, red) and labeling of cell nuclei (with Hoechst, b...
The spatiotemporal pattern of cerebral amyloid deposition, detectable as light microscopically recog...
Purpose. 18F-FC119S is a positron emission tomography (PET) tracer for imaging β-amyloid (Aβ) plaque...
<p>Immunohistochemical staining of β-amyloid plaques using A) anti-Aβ (1–42) polyclonal antibody B) ...
<p><b>A</b>) Western blot with the antibody M3.2 (specific for rodent β-amyloid) using hippocampal t...
<p>Abscissa, categorized groups of experimental animals. Ordinate, ELISA-estimated amount of mouse β...
<p><b>A</b>, Age-dependent decrease of percentage of plaque-free transgenic 5XFAD mice treated with ...
<p>Brain sections from mice injected with targeted liposomes (<b>A, D, G, J</b>) were probed with tw...
<p>The left column shows staining in the MEC region of MPS IIIB (−/−) mice, with the middle and righ...
<p><b>A.</b> Levels of Aβ in brain tissue were determined using monoclonal antibody 4G8 that recogni...
<p>Coronal brain sections from 22-week-old wild-type control littermates (A, C, E) and 5XFAD transge...
<p>YM3711 at a dose of 100 µg was injected weekly to 15-month old model mice for 6 weeks and the bra...
<p>(<b>A–C</b>) Representative half brain sections of WT mice, vehicle or SS-treated APP/PS1 mice st...
<p>Sections prepared from the hippocampus (A, D, G, J, K, M) and the cortex (B, E, H), of a 12 month...
<p><b>Abscissa</b>, age of mice (month); <b>ordinate</b>, plaque density (n/mm<sup>2</sup>) in view ...
<p>(A) Immunostaining of Aβ peptide (anti-Aβ 6E10, red) and labeling of cell nuclei (with Hoechst, b...
The spatiotemporal pattern of cerebral amyloid deposition, detectable as light microscopically recog...
Purpose. 18F-FC119S is a positron emission tomography (PET) tracer for imaging β-amyloid (Aβ) plaque...
<p>Immunohistochemical staining of β-amyloid plaques using A) anti-Aβ (1–42) polyclonal antibody B) ...
<p><b>A</b>) Western blot with the antibody M3.2 (specific for rodent β-amyloid) using hippocampal t...