¹⁹F-PLGA labeled cells remain detectable over time and upon cell division, although label intensity decreases.

<p>Fluorescence histograms for CellTrace and ¹⁹F -PLGA-labeled CD34⁺ cells <b>(</b>A) Population shown is labeled cells at day 0. Horizontal axes show the intensity of the CellTrace Violet signal (left panel) and of the FITC signal, representing the ¹⁹F -PLGA nanoparticles (right panel). (B) Population shown is labeled cells after 4 days of culture. The horizontal axes show the intensity of the CellTrace Violet signal, indicating the number of cell divisions. (C) Populations shown are labeled cells after 4 days of culture who had undergone 0, 1, 2 or 3 cell division respectively (depicted in the panels from left to right). Horizontal axes show the intensity of the FITC signal, representing the ¹⁹F -PLGA nanoparticles.