Expression Profiling of Individual Genes in Pigs with Divergent Severity of Influenza Pathology.

<p>(A) Scatter plot of fold changes for 18 genes in the ‘Susceptible’ (SUS) relative to ‘Resilient’ (RES) group of pigs measured by two different methods: microarray hybridization (X-axis) and RT-qPCR (Y-axis). The Pearson Correlation coefficient of the two variables is shown. The 18 genes were identified as DEGs by microarray and the expression pattern was confirmed for 15/18 genes (<i>P</i><0.05). Overall the two measures of expression differences are highly correlated, indicating that there is generally good agreement between fold changes of DEGs measured by each method. (B) Fold change in SUS relative to RES pigs of a panel of cytokine genes as measured by microarray and RT-qPCR. Statistically significant fold changes are denoted with an asterix (*<i>P</i><0.05).