Correlation between relaxometric and histological markers of disease severity.

<p>Disease severity as assessed by the METAVIR score <b>(A)</b> and the area fraction stained with Sirius Red for collagen <b>(B)</b> increases mainly 6 weeks after infection. The area fraction of liver T₂ values between 16 and 26 ms obtained at 10 weeks after infection correlates with the METAVIR grading (<b>C</b>) and fibrosis quantification with Sirius Red staining (<b>D</b>). A 95% bivariate normal density ellipse is represented on each scatterplot. (The correlations obtained for the values measured at 6 and 10 weeks are shown in <a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0004036#pntd.0004036.s002" target="_blank">S2A and S2B Fig</a>).