MnTBAP treatment improves insulin-assisted glucose tolerance (IAGT) in mice fed a HFD.

<p>Mice were simultaneously injected with 2.0 U/Kg insulin and 2.0 g/Kg glucose and blood glucose values were assessed at baseline and 20, 40, and 60 min following the injection (Panels A) and the area under the IAGT curve was calculated (Panels B). *, Denotes statistically significant difference from HFD-Vehicle. ⁺, Denotes statistically significant difference from LFD-Vehicle mice. N = 7–14 mice per group.