TVV+MM protects mice against avian H7N7.

<p>Mice (n = 10/group) were immunized 1x or 2x with TVV with or without MM. Four weeks later, mice were challenged with 25xLD₅₀ H7N7 A/Chicken/Netherlands/62155710/03 and monitored for 21 days for survival, body weight loss and clinical symptoms. Graphs represent the Kaplan-Meier survival curve (A and D) or mean bodyweight change with 95% confidence interval (B and E) or mean clinical scores with interquartile range (C and F). Asterisks indicate statistically significant differences compared to the vehicle control group (*<i>p</i><0.05, **<i>p</i><0.01, ***<i>p</i><0.001, according to the materials and methods section).