Depletion of the M2 cardiac macrophage populations following 1 week GW2580 treatment.
- Anne-Laure Leblond (800296)
- Kerstin Klinkert (800297)
- Kenneth Martin (380811)
- Elizebeth C. Turner (380812)
- Arun H. Kumar (800298)
- Tara Browne (800299)
- Noel M. Caplice (380815)
Publication date
September 2015
DOIAbstract
<p>A. Representative profiles of digested hearts from vehicle and GW2580-treated animals. B. Quantification of cardiac tissue-resident macrophages 1 week post-GW2580 treatment (n = 6 animals per group). C. Quantification of CD206<sup>+</sup> M2 macrophages within the heart, 1 week post-GW2580 treatment (n = 6 animals per group, nd:not detected). D. mRNA expression relative to GAPDH of M2 markers Arg1 and CD206 and E. M1 markers IL6, IL1β, respectively, within the heart following 1 week GW2580 treatment (n = 4 animals per group). * <i>p</i><0.05, ** <i>p</i><0.01.</p
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