<p>(A) Hypoxia insult caused decline in cell viability (20%) compared to normoxia control cells by 24 h. (B) Nanocurcumin treatment at 500 ng/ml significantly improved cellular viability (89%) by 24 h of hypoxia exposure and confirmed by FACS. Curcumin treatment did not show significant improvement in cellular viability at any time point. No significant change in cell viability was observed in nanocurcumin or curcumin treated cells under normoxia. Nanocurcumin treatment at 500 ng/ml was used for further experiments. Values are mean ± SD, significant values represented as <sup>@@</sup>p≤0.01 <i>vs</i> normoxia and <sup>#</sup>p≤0.01 <i>vs</i> hypoxia. Non-significant changes are designated as ns.</p
Background and objective This study was designed to compare the efficacy of curcumin (CRN) with that...
Curcumin is a polyphenol extracted from the Curcuma plant. Curcumin has been used widely in ayu...
Curcumin (CM) possesses multiple biological activities. However, poor water solubility and low bioav...
<p>(A) Hypoxia insult disrupted ΔΨ<sub>m</sub> as early as 1 h of exposure caused in HVCM cells as d...
<p>Hypoxia stress disturbed cellular redox balance as depicted by increase in ROS leakage and lipid ...
<p>Hypoxia insult prevented c-Fos and c-Jun expression in HVCM cells upto 24 h of hypoxia and thus p...
<p>(A) MnSOD activity showed gradual decline with increment of duration of hypoxia as shown by fluor...
<p>Histone acetylation by p-300 was up-regulated with a corresponding decline in HDAC activity in ca...
Hypoxia induced oxidative stress incurs pathophysiological changes in hypertrophied cardiomyocytes b...
<div><p>Hypoxia induced oxidative stress incurs pathophysiological changes in hypertrophied cardiomy...
Cells were stimulated with curcumin (0, 5, 10, 20 μM) for 20 h or 16 h. The positive control group a...
Objective: Cellular damage induced by oxidative stress has been involved in the development of neuro...
<p>The dependency of translocation of p53 to mitochondria on induction of hypertrophy in HVCM cells ...
In this study, several formulations of nanoceria and dextran-nanoceria with curcumin, each demonstra...
International audienceBackground: Chronic intermittent hypoxia (IH), the hallmark feature of obstruc...
Background and objective This study was designed to compare the efficacy of curcumin (CRN) with that...
Curcumin is a polyphenol extracted from the Curcuma plant. Curcumin has been used widely in ayu...
Curcumin (CM) possesses multiple biological activities. However, poor water solubility and low bioav...
<p>(A) Hypoxia insult disrupted ΔΨ<sub>m</sub> as early as 1 h of exposure caused in HVCM cells as d...
<p>Hypoxia stress disturbed cellular redox balance as depicted by increase in ROS leakage and lipid ...
<p>Hypoxia insult prevented c-Fos and c-Jun expression in HVCM cells upto 24 h of hypoxia and thus p...
<p>(A) MnSOD activity showed gradual decline with increment of duration of hypoxia as shown by fluor...
<p>Histone acetylation by p-300 was up-regulated with a corresponding decline in HDAC activity in ca...
Hypoxia induced oxidative stress incurs pathophysiological changes in hypertrophied cardiomyocytes b...
<div><p>Hypoxia induced oxidative stress incurs pathophysiological changes in hypertrophied cardiomy...
Cells were stimulated with curcumin (0, 5, 10, 20 μM) for 20 h or 16 h. The positive control group a...
Objective: Cellular damage induced by oxidative stress has been involved in the development of neuro...
<p>The dependency of translocation of p53 to mitochondria on induction of hypertrophy in HVCM cells ...
In this study, several formulations of nanoceria and dextran-nanoceria with curcumin, each demonstra...
International audienceBackground: Chronic intermittent hypoxia (IH), the hallmark feature of obstruc...
Background and objective This study was designed to compare the efficacy of curcumin (CRN) with that...
Curcumin is a polyphenol extracted from the Curcuma plant. Curcumin has been used widely in ayu...
Curcumin (CM) possesses multiple biological activities. However, poor water solubility and low bioav...