Immunohistochemical analysis and quantification of CD8-positive T lymphocytes in human lung cancer.

<p>Human lung cancer tissue array was stained with CD8 antibody to detect cytotoxic T lymphocytes. (A) Quantification of CD8⁺ cells in lung cancer vs. healthy donor specimens. (B–E) Quantification of CD8⁺ cells based on (B) their pathology, (C) cancer stage, (D) tumor size, and (E) nodal status. Cell numbers are given as CD8-positive cells per 1000 cells. (F) Representative images of human lung sections stained with CD8 antibody based on their pathology. Scale bar = 25 μm.