Cardiac hypertrophy occurred in the embryos of STZ-induced diabetic mice.

<p><b>A-B</b>: The representative mice from the control (A) and PGDM groups (B). <b>C</b>: The bar charts showing the levels of blood glucose in the control and PGDM mice before and after STZ injection. <b>D</b>: The graph showing the levels of blood glucose in the control and PGDM mice from E0.5 to E18.5 after fertilization. <b>E-F</b>: The representative images from M-type ultrasound of fetal mouse hearts in the control (E) and PDGM groups (F). The red arrows indicate the thickness of the LVPW, and the white arrows indicate the left ventricular internal diameter. <b>G</b>: The bar charts showing the thicknesses of the cardiac RVAW, IVS and LVPW in the control and PGDM mice at E18.5 after fertilization. <b>H</b>: The bar charts showing the diameters of the ventricular cavities in the control and PGDM mice at E18.5 after fertilization. <b>I</b>: The bar charts showing the stroke volume in the control and PGDM mice at E18.5 after fertilization. <b>J</b>: The bar charts showing the ejection fraction in the control and PGDM mice at E18.5 after fertilization. *<i>P</i><0.05, **<i>P</i><0.01, ***<i>P</i><0.001 vs control. Scale bars: 1 cm in A-B and 500 μm in E-F.