Cell viability and combination index of BGC-823 and SGC-7901 treated with a drug combination.

<p>Panel (A, B and C) represents growth inhibition in BGC-823 and SGC-7901 cells with a combination of HPRP-A2 (6 μM) and DOX (1.6 μg/ml) after incubation for 4, 24 and 48 hours, respectively. Results are expressed as the percentage of the control ± SD of three independent experiments. Panel D shows combination index (Q) of the combination treatment of HPRP-A2 and DOX, where Q<0.85, Q>1.15 and 0.85