Expression of renalase in glomerular macrophages in active proliferative LN.

<p>(A) Left panel—kidney immunohistochemical staining for renalase of a control subject (20X); Right panel kidney immunohistochemical staining for renalase of an active LN patient (20X), arrows indicate representative renalase expression in glomeruli; (B) immunofluorescent staining of representative kidney sections of a patient with active LN, Left panel–staining with anti-CD68 antibody, Middle left- staining with anti-renalase antibody, Middle right -: nuclear staining, Right panel- merged picture; (C) immunofluorescent staining of representative kidney sections of a patient with active LN, Left panel—staining with anti-CD34 antibody, Middle left—staining with anti-renalase antibody, Middle right-: nuclear staining, Right panel—merged picture; (D) immunofluorescent staining of THP–1 cells in culture; Left panel—staining with anti-CD68 antibody, Middle left—staining with anti-renalase antibody, Middle right-: nuclear staining, Right panel—merged picture.