<p>Note: The mutated amino acids are underlined; “-” indicates residues deletion; “NB” means not binding.</p><p>Significant decreases in binding affinity relative to Wt from genotype I are shown in bold.</p><p>Amino acid sequences of DENV-4 ED3 mutants and relative dissociation constants compared to wild-type (Wt) rED3.</p
(A) Binding of SAM to native or refolded DENV3 MTase mutants (H110A, E111A, E112A, H110A/E111A or H1...
(A) Binding of SAM to native or refolded DENV3 MTase mutants (H110A, E111A, E112A, H110A/E111A or H1...
<p>Non-synonymous amino acid mutations that distinguish the KW DENV-1 strain.</p
<p><b>Footnote:</b> AA: Amino acid, C-IA: Cosmopolitan IA, C-IB: Cosmopolitan IB, C-II: Cosmopolitan...
<p>Comparison of apparent dissociation constants (K<sub>d</sub>) from ssDNA of A3G and A3F wild-type...
<p>Comparison of amino acid sequences of peptides B2, B16, B29, B38, B45, B64 and B19 between the fo...
<p>Amino acid substitutions between 201610225, DENV-3 prototype strain (H87), and DENV-3 Indonesian ...
<p>A panel of 54 DENV1 RVP variants containing single, double, or triple amino acid changes was cons...
<p>Amino acid differences in reovirus proteins of the <i>jin</i> mutants and the <i>wt</i> T3D reovi...
Solution behaviors of DENV3 and ALSV mutant MTase proteins on a Superdex 200 Increase 10/300 GL colu...
<p>Binding assays (ELISA) of representative mutants for the four DenV serotypes are shown; higher y ...
<p>Identical amino acids among all four DENV were shown in dot. Asterisks denote residues that have ...
<p>E, envelope; NS2A and NS5, nonstructural proteins 2A and 5. * Denotes a frequency above 50%.</p
<p>Polar and non-polar amino acids are coded as follows: hydrophobic in pink (Ala, Phe, Ile, Leu, Me...
(A) Binding of SAM to native or refolded DENV3 MTase mutants (H110A, E111A, E112A, H110A/E111A or H1...
(A) Binding of SAM to native or refolded DENV3 MTase mutants (H110A, E111A, E112A, H110A/E111A or H1...
(A) Binding of SAM to native or refolded DENV3 MTase mutants (H110A, E111A, E112A, H110A/E111A or H1...
<p>Non-synonymous amino acid mutations that distinguish the KW DENV-1 strain.</p
<p><b>Footnote:</b> AA: Amino acid, C-IA: Cosmopolitan IA, C-IB: Cosmopolitan IB, C-II: Cosmopolitan...
<p>Comparison of apparent dissociation constants (K<sub>d</sub>) from ssDNA of A3G and A3F wild-type...
<p>Comparison of amino acid sequences of peptides B2, B16, B29, B38, B45, B64 and B19 between the fo...
<p>Amino acid substitutions between 201610225, DENV-3 prototype strain (H87), and DENV-3 Indonesian ...
<p>A panel of 54 DENV1 RVP variants containing single, double, or triple amino acid changes was cons...
<p>Amino acid differences in reovirus proteins of the <i>jin</i> mutants and the <i>wt</i> T3D reovi...
Solution behaviors of DENV3 and ALSV mutant MTase proteins on a Superdex 200 Increase 10/300 GL colu...
<p>Binding assays (ELISA) of representative mutants for the four DenV serotypes are shown; higher y ...
<p>Identical amino acids among all four DENV were shown in dot. Asterisks denote residues that have ...
<p>E, envelope; NS2A and NS5, nonstructural proteins 2A and 5. * Denotes a frequency above 50%.</p
<p>Polar and non-polar amino acids are coded as follows: hydrophobic in pink (Ala, Phe, Ile, Leu, Me...
(A) Binding of SAM to native or refolded DENV3 MTase mutants (H110A, E111A, E112A, H110A/E111A or H1...
(A) Binding of SAM to native or refolded DENV3 MTase mutants (H110A, E111A, E112A, H110A/E111A or H1...
(A) Binding of SAM to native or refolded DENV3 MTase mutants (H110A, E111A, E112A, H110A/E111A or H1...
<p>Non-synonymous amino acid mutations that distinguish the KW DENV-1 strain.</p