Dm Slo currents are blocked by the BK channel antagonists verruculogen and penitrem A.
- Anna Crisford (803573)
- Ulrich Ebbinghaus-Kintscher (803574)
- Eva Schoenhense (803575)
- Achim Harder (225279)
- Klaus Raming (803576)
- Ita O’Kelly (803577)
- Kelechi Ndukwe (803578)
- Vincent O’Connor (286285)
- Robert J. Walker (723250)
- Lindy Holden-Dye (149727)
Publication date
October 2015
DOIAbstract
<p>Top panel shows representative traces of Dm Slo whole cell currents stable expressed in CHO cells before and after verruculogen (3μM) application. Membrane potential was held at -70mV and stepped to between -120 and +60mV in 10mV increments for 100ms. Bottom panel shows dose-response curves for verrucologen (circles) and penitrem A (squares) on Dm Slo. Membrane potential was held at -70mV. Test pulses to + 60mV for 100ms. Each data points represent the mean ± s.e. of n = 3 cells.</p
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