Scintigraphic acquisition of athymic Nude mice bearing CD20+ (R) and CD20- (L) xenografts.

<p>Mice were grafted with tumor CD20+ on right flank (R, dark gray arrow) and CD20- on left flank (L, light gray head arrow). Mice were injected intravenously with 35–37 MBq of ^99mTc anti-CD20 IgG-SH (A), ^99mTc anti-EGFR IgG-SH (B) or ^99mTc-anti-IsoLink^® (C). Mice were anesthetized with isoflurane (2%, under O₂ conditions, 1 L/min). Static imaging was acquired, 24h after injection, with a gamma camera (dual-head system fitted with low-energy parallel collimators, 256 × 256 pixels, zoom 2, 10 minutes acquisition).