ERK1/2 mice have increased numbers of hematopoietic stem cells (LSK cells), common lymphoid progenitors, and granulocyte-macrophage progenitors on <i>ex vivo</i> flow cytometry analysis of progenitor populations.

<p>(A) Bone marrow cells from LysM and ERK1/2 mice (six of each) were counted using a hemacytometer and then analyzed by flow cytometry using the indicated gating strategy and the antibody panel described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0140064#pone.0140064.t001" target="_blank">Table 1</a>. (B-F) Cell numbers from each population of immature hematopoietic cells were extrapolated from the total bone marrow cell counts and the percentage of each population following analysis in FlowJo. Data are represented as means ± standard deviations. Results are representative of two independent experiments.