P2Y12R blockade reduces the area of the hepatic inflammatory infiltrate in a murine model of <i>S</i>. <i>mansoni</i> infection.

<p>Representative granuloma images from infected mice (Ai) untreated or (Aii) treated with clopidogrel. Slide sections were stained with hematoxylin-eosin and examined under a light microscope. (B) The individual granuloma area was estimated from 10–20 granulomas acquired for each individual mouse. Data represent the mean ± SE and were analyzed by Student’s <i>t</i> test. (*p<0.05). <i>n</i> = 5–8 mice/group and represents animals from at least 2 independent infection studies.