Crystal Structure of DIM-1.

<p>A. Overall fold of the enzyme. Protein backbone is color-ramped from blue (N-) to red (C-terminus). Active site residues are rendered as sticks (carbon atoms in green, other atom colors as standard). Zinc ions (gray) and water molecules (red) are shown as spheres. B. Superposition of B1 MBL structures: DIM-1 (green); BcII (pdb accession 1BC2 ([<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0140059#pone.0140059.ref043" target="_blank">43</a>], blue); IMP-1 (1DDK [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0140059#pone.0140059.ref023" target="_blank">23</a>], teal); VIM-2 (1KO3 [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0140059#pone.0140059.ref044" target="_blank">44</a>], magenta); BlaB (1M2X [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0140059#pone.0140059.ref045" target="_blank">45</a>], dark green); CcrA (1ZNB [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0140059#pone.0140059.ref046" target="_blank">46</a>], yellow); NDM-1 (3Q6X [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0140059#pone.0140059.ref041" target="_blank">41</a>], cyan); IND-7 (3L6N [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0140059#pone.0140059.ref047" target="_blank">47</a>], red) and GIM-1 (2YNT [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0140059#pone.0140059.ref048" target="_blank">48</a>], orange). This Figure was generated using Pymol (<a href="http://www.pymol.org" target="_blank">www.pymol.org</a>).