EBNA1 sequence variations in four groups of lymphoma.

<p>The numbers across the top correspond to the amino acid positions under which the B95-8 prototype amino acid and nucleotide sequence are listed. Different patterns are noted to the left column, while the specimens showing identical sequences to each other are listed by a representative isolate in the second column. The followed numbers in the parentheses denote the amount of the identical sequences from NK/T, HL, DLBCL, and T cell lymphoma, respectively. The small letters denote the nucleotide, and the amino acids are denoted by capital letters. NK: nasal natural killer/T cell lymphoma; HL: Hodgkin’s lymphoma; DL: diffuse large B cell lymphoma; T: T cell lymphoma. Some rare sporadic mutations are not shown in Fig 1.