RelA levels vary widely in breast cancer and negatively correlate with proliferation in certain subtypes.

<p><b>A.</b> Representative images of breast tumors with each RelA staining profile: cytoplasm low/high; nuclear positive/negative. Red arrows indicate positive nuclei and scale bar = 100μM. <b>B.</b> The table shows number of tumors (divided by ER and HER2 based subtypes) within each category of RelA staining pattern in the Boston-cohort (n = 105) and the Croatia-cohort (n = 198). The Fishers exact test (FET) p-values for the distribution is indicated. <b>C.</b> Box plot showing the distribution of the percentage of Ki67 positive nuclei within each category of breast tumors based on RelA staining. Nuclear negative/cytoplasm high (nNcH), nuclear negative/cytoplasm low (nNcL) and nuclear positive/cytoplasm high (nPcH). The Wilcoxon rank sum test was used to estimate the significance of the association and the p-values are indicated.