Histology.

<p>Haematoxylin and eosin stained corneal sections, comparing vancomycin prophylaxis to non-prophylaxis cases. A. Healthy cornea. B (day 2, prophylaxis). A rich infiltration of neutrophils is present throughout the stroma. The epithelial and endothelial surfaces are irregular due to stromal oedema. C (day 2, non-prophylaxis). The stroma appears more oedematous than in image B. A rich neutrophilic infiltration is also present, mostly in the pocket, but the neutrophils appear to be less densely arranged in the stroma than in image B, most likely reflecting the presence of more oedema. D (day 4, prophylaxis). The stroma is more oedematous than in image B and the Descemets membrane is detached, reflecting greater levels of infection. The neutrophilic infiltration is not as dense as in image B, most likely due to more stromal oedema. E (day 4, non-prophylaxis). The stroma appears similarly oedematous to that in image D and slightly richer in neutrophilic infiltration. (Scale bar 100μm)