Elucidating the underlying mechanism of the cellular physiological activities at the molecular level is currently an important research topic in life sciences. The invention of the atomic force microscopy (AFM) provided new methods for acquiring new cognition about cellular chemical processes. With the use of AFM, the specific recognition interaction between CD20 antigen and rituximab antibody on B lymphoma cells was explored under near-physiological conditions. The high quality AFM images of B lymphoma cells were acquired and the CD20-rituximab complex binding force was measured by AFM single-molecule force spectroscopy (SMFS). The experimental results provide new insights for understanding the CD20-rituximab specific interaction and lay t...
Knowledge of drug-target interaction is critical to our understanding of drug action and can help de...
Rituximab, a monoclonal antibody against the CD20 molecule expressed on B cells, has revolutionized ...
The wide applications of atomic force microscopy (AFM) in the past decade have contributed much to t...
Elucidating the underlying mechanism of the cellular physiological activities at the molecular level...
Elucidating the underlying mechanisms of cell physiology is currently an important research topic in...
The invention of atomic force microscopy (AFM) provides new technology for measuring the molecular s...
Atomic force microscopy (AFM) offers an exciting tool for quantitatively investigating the physiolog...
The invention of atomic force microscopy(AFM) has provided new technology for measuring specific mol...
Illuminating the underlying mechanism of drug action at single-cell and single-molecule levels is of...
The invention of atomic force microscopy (AFM) provides new technology for investigating the physiol...
The treatment of Non-Hodgkin's lymphoma (NHL) was revolutionized by the approval of rituximab in 199...
Summary Atomic force microscopy (AFM) provides a new technology to visualize the cellular topography...
Atomic force microscopy (AFM) was used to locate CD20 molecules on the surface of lymphoma Raji cell...
Knowledge of drug-target interaction is critical to our understanding of drug action and can help de...
Rituximab, a monoclonal antibody against the CD20 molecule expressed on B cells, has revolutionized ...
The wide applications of atomic force microscopy (AFM) in the past decade have contributed much to t...
Elucidating the underlying mechanism of the cellular physiological activities at the molecular level...
Elucidating the underlying mechanisms of cell physiology is currently an important research topic in...
The invention of atomic force microscopy (AFM) provides new technology for measuring the molecular s...
Atomic force microscopy (AFM) offers an exciting tool for quantitatively investigating the physiolog...
The invention of atomic force microscopy(AFM) has provided new technology for measuring specific mol...
Illuminating the underlying mechanism of drug action at single-cell and single-molecule levels is of...
The invention of atomic force microscopy (AFM) provides new technology for investigating the physiol...
The treatment of Non-Hodgkin's lymphoma (NHL) was revolutionized by the approval of rituximab in 199...
Summary Atomic force microscopy (AFM) provides a new technology to visualize the cellular topography...
Atomic force microscopy (AFM) was used to locate CD20 molecules on the surface of lymphoma Raji cell...
Knowledge of drug-target interaction is critical to our understanding of drug action and can help de...
Rituximab, a monoclonal antibody against the CD20 molecule expressed on B cells, has revolutionized ...
The wide applications of atomic force microscopy (AFM) in the past decade have contributed much to t...