The serum Levels of anti-dsDNA, -nucleosome and -histone antibodies in SLE patients.

<p><b>(A)</b> Serum levels of 3-pos and non 3-pos LN patients when they had active disease. <b>(B)</b> Serum levels of anti-dsDNA, -nucleosome, and -histone Abs in 3-pos SLE patients with/without LN. <b>(C)</b> Significantly higher titers of the three anti-nucleosome antibodies in 3-pos LN patients, compared to that in 2-pos or 1-pos cohorts. 3-pos: co-positivity of anti-dsDNA, -nucleosome, and -histone Abs; 2-pos: anti-dsDNA and -nucleosome, or anti-dsDNA and -histone, or anti -nucleosome and -histone; 1-pos: anti-dsDNA, or anti-nucleosome, or anti-histone. The antibody reactivity was determined by Euroline ANA profile (IgG).