Expression of miR-17, miR-21, miR-145, miR-125, miR-200b, and miR-126 as obtained in the study of the test cases.

<p><b>(A & B)</b> miR-17 in normal (N) and adenomatous (A) tissue and in adenocarcinoma (AC); <b>(C & D)</b> miR-21 expression in stroma of the adenoma compared to normal tissue and in the cancer-associated stroma cells(*). A small group of positive tumour epithelial cells is also present (white arrow); <b>(E)</b> miR-145 is seen in smooth muscle cells (arrow) and vascular smooth muscle cells (arrowhead); in the magnification (<b>F</b>) a reduced number of miR-145 positive fibroblast-like cells are found in the adenoma (arrow) compared to normal tissue (arrowhead); <b>(G)</b> Faint miR-125b signal was seen in the muscularis mucosa (mm); <b>(H)</b> miR-200b was seen in the epithelial cells at base of the crypts, but in this case also in the epithelial cancer cells; <b>(I)</b> miR-126 is exclusively seen in the endothelial cells; <b>(J)</b> The scramble probe showed only discrete background staining.