ARQ 092 inhibits AKT signaling in AN3CA mouse xenografts, <i>In Vivo</i>.
- Yi Yu (28902)
- Ronald E. Savage (813914)
- Sudharshan Eathiraj (813915)
- Justin Meade (813916)
- Michael J. Wick (813917)
- Terence Hall (813918)
- Giovanni Abbadessa (486595)
- Brian Schwartz (767427)
Publication date
October 2015
DOIAbstract
<p>(A) Tumor samples were assessed by IHC for p-AKT(S473) and p-PRAS40(T246). Veh: Vehicle. (B) p-AKT(S473) and (T308), and p-PRAS40(T246) were assessed by western blot analysis from tumor tissues from and AN3CA mouse xenograft after treatment with 100 or 200 mg/kg. The percentage remaining of the phosphorylated proteins is shown and the vehicle group was designated as 100%.</p
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