<p>This plot of the trajectories of 4 kinetic model metabolite concentrations over time shows that simulation initiated a small distance away from the steady state allowed the system to relax back onto the Keio steady state (dashed horizontal lines), also proving the state to be stable. Concentrations of all other metabolites also relaxed back onto their respective Keio steady state values, a metabolic profile referred to as the Keio phenotype.</p
<p>Normalization of the pathway-specific stoichiometric matrix with respect to steady state concent...
Recently structural kinetic modeling has been proposed as an intermediary approach between a full ki...
Computer assisted analysis and simulation of biochemical pathways can improve the understanding of t...
<p>Plots along left illustrate the convergence of the model metabolite concentrations (solid lines) ...
Steady state concentrations of selected metabolites as functions of ξ, for the simulations of the CH...
<p>Percentage Increase in Steady State Metabolite Concentrations, from the Keio Phenotype to the Alt...
Integration of different kinds of biological networks, is within the holistic approach of Systems B...
Simulation of metabolic systems with kinetic models requires a large number of parameter values, whi...
<p>The model was simulated for and various values of , the initial concentration of STU, as shown, ...
A defining characteristic of living cells is the ability to respond dynamically to external stimuli ...
Artículo de publicación ISIDynamic models of metabolism are instrumental for gaining insight and pre...
textabstractThe steady-state assumption, which states that the production and consumption of metabol...
<p>We repeated each simulation 11 times to generate a sample of simulation variability, with some si...
Metabolic response coecients describe how dynamic properties of metabolic systems- like steady state...
Motivation The understanding of metabolic interactions has grown rapidly in recent years with metab...
<p>Normalization of the pathway-specific stoichiometric matrix with respect to steady state concent...
Recently structural kinetic modeling has been proposed as an intermediary approach between a full ki...
Computer assisted analysis and simulation of biochemical pathways can improve the understanding of t...
<p>Plots along left illustrate the convergence of the model metabolite concentrations (solid lines) ...
Steady state concentrations of selected metabolites as functions of ξ, for the simulations of the CH...
<p>Percentage Increase in Steady State Metabolite Concentrations, from the Keio Phenotype to the Alt...
Integration of different kinds of biological networks, is within the holistic approach of Systems B...
Simulation of metabolic systems with kinetic models requires a large number of parameter values, whi...
<p>The model was simulated for and various values of , the initial concentration of STU, as shown, ...
A defining characteristic of living cells is the ability to respond dynamically to external stimuli ...
Artículo de publicación ISIDynamic models of metabolism are instrumental for gaining insight and pre...
textabstractThe steady-state assumption, which states that the production and consumption of metabol...
<p>We repeated each simulation 11 times to generate a sample of simulation variability, with some si...
Metabolic response coecients describe how dynamic properties of metabolic systems- like steady state...
Motivation The understanding of metabolic interactions has grown rapidly in recent years with metab...
<p>Normalization of the pathway-specific stoichiometric matrix with respect to steady state concent...
Recently structural kinetic modeling has been proposed as an intermediary approach between a full ki...
Computer assisted analysis and simulation of biochemical pathways can improve the understanding of t...