Spine morphology of CA3 basal dendrites.

<p>(A) Graphical representation of spine density/30μm of basal dendrites of CA3 subarea; (B) Representative images of DIL dye staining of basal dendrites of CA3 subarea (scale bar = 20 μm);(C) Graphical representation of percentage of branched, thin, mushroom and stubby spines per total spines of basal dendrites of CA3 subarea; (D) Negative Spearman Correlation of spine density/30μm of basal dendrites of CA3 subarea with working memory error (WME) (r = -0.72, p = 0.04); (E) Negative Spearman correlation of spine density/30 μm of basal dendrites of CA3 subarea with latency (r = -0.78, p = 0.01, r ranges from -1 to 0 to +1 where -1 = 100% negative correlation, 0 = no correlation and +1 = 100% positive correlation); (J) Negative Spearman Correlation of spine density/30μm of basal dendrites of CA3 subarea with reference memory error (r = -0.71, p = 0.04); Statistical evaluation was carried out by multi-comparison one-way ANOVA followed by post-hoc Bonferroni's test. Data is provided as mean±SD (*P < 0.05;**P ≤ 0.01 ***P < 0.001; ****P < 0.0001)].