Ly-GDI over-expression leads to reduced IgG immune complex-induced production of C5a in BAL fluids.

<p>Adeno-GFP or Adeno-Ly-GDI was injected to mice <i>via</i> an airway instillation at a dose of 5 × 10⁸ PFU. 3 days later, the mice were subjected to IgG immune complex-induced lung injury or control treatment (αBSA only). Cell-free BAL fluids were harvested 4 h later, and ELISA was conducted to measure the C5a content. Data were expressed as means ± S. E. M. N ≥ 3 mice for each group. * indicated statistically significant difference- <i>p</i> < 0.05.