<div><p>During the first divisions of the female mouse embryo, the paternal X-chromosome is coated by <i>Xist</i> non-coding RNA and gradually silenced. This imprinted X-inactivation principally results from the apposition, during oocyte growth, of an imprint on the X-inactivation master control region: the X-inactivation center (<i>Xic</i>). This maternal imprint of yet unknown nature is thought to prevent <i>Xist</i> upregulation from the maternal X (X<sup>M</sup>) during early female development. In order to provide further insight into the X<sup>M</sup> imprinting mechanism, we applied single-cell approaches to oocytes and pre-implantation embryos at different stages of development to analyze the expression of candidate genes within the...
X inactivation is the mammalian method for X-chromosome dosage compensation, but some features of th...
The Xist (X-inactive specific transcript) gene, which maps to the X-inactivation centre (Xic), is ex...
X chromosome inactivation (XCI) is the mammalian mechanism that compensates for the difference in ge...
During the first divisions of the female mouse embryo, the paternal X-chromosome is coated by Xist n...
AbstractIn marsupials and in extraembryonic tissues of placental mammals, X inactivation is imprinte...
The long noncoding RNA Xist is expressed from only the paternal X chromosome in mouse preimplantatio...
<div><p>Mammalian development is strongly influenced by the epigenetic phenomenon called genomic imp...
Imprinted X-inactivation is a paradigm of mammalian transgenerational epigenetic regulation resultin...
XX female mammals undergo transcriptional silencing of most genes on one of their two X-chromosomes ...
AbstractX chromosome inactivation (XCI) is the phenomenon through which one of the two X chromosomes...
SummaryX inactivation is controlled by Xist and its antisense gene, Tsix, neither of which encodes a...
Transcriptional silencing of the human inactive X chromosome is induced by the XIST gene within the ...
Mammalian development is strongly influenced by the epigenetic phenomenon called genomic imprinting,...
Mammalian development is strongly influenced by the epigenetic phenomenon called genomic imprinting,...
During mouse embryogenesis, reversion of imprinted X chromosome inactivation in the pluripotent inne...
X inactivation is the mammalian method for X-chromosome dosage compensation, but some features of th...
The Xist (X-inactive specific transcript) gene, which maps to the X-inactivation centre (Xic), is ex...
X chromosome inactivation (XCI) is the mammalian mechanism that compensates for the difference in ge...
During the first divisions of the female mouse embryo, the paternal X-chromosome is coated by Xist n...
AbstractIn marsupials and in extraembryonic tissues of placental mammals, X inactivation is imprinte...
The long noncoding RNA Xist is expressed from only the paternal X chromosome in mouse preimplantatio...
<div><p>Mammalian development is strongly influenced by the epigenetic phenomenon called genomic imp...
Imprinted X-inactivation is a paradigm of mammalian transgenerational epigenetic regulation resultin...
XX female mammals undergo transcriptional silencing of most genes on one of their two X-chromosomes ...
AbstractX chromosome inactivation (XCI) is the phenomenon through which one of the two X chromosomes...
SummaryX inactivation is controlled by Xist and its antisense gene, Tsix, neither of which encodes a...
Transcriptional silencing of the human inactive X chromosome is induced by the XIST gene within the ...
Mammalian development is strongly influenced by the epigenetic phenomenon called genomic imprinting,...
Mammalian development is strongly influenced by the epigenetic phenomenon called genomic imprinting,...
During mouse embryogenesis, reversion of imprinted X chromosome inactivation in the pluripotent inne...
X inactivation is the mammalian method for X-chromosome dosage compensation, but some features of th...
The Xist (X-inactive specific transcript) gene, which maps to the X-inactivation centre (Xic), is ex...
X chromosome inactivation (XCI) is the mammalian mechanism that compensates for the difference in ge...