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LDA-Mediated Synthesis of Triarylmethanes by Arylation of Diarylmethanes with Fluoroarenes at Room Temperature

  • Xinfei Ji (1508608)
  • Tao Huang (110613)
  • Wei Wu (27708)
  • Fang Liang (517551)
  • Song Cao (17001)
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Publication date
October 2015
Icon DOI
10.1021/acs.orglett.5b02602.s001

Abstract

A practical and convenient approach for the secondary C­(sp<sup>3</sup>)–H arylation of diarylmethanes with various fluoroarenes is described. The reaction proceeds smoothly in the presence of LDA (lithium diisopropylamide) at room temperature and affords triarylmethanes in moderate to high yields

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