Extracellular acidosis impairs the active intrinsic properties of the cortical GABAergic neurons dominantly.

<p><b>A)</b> shows the differences of spike frequencies between control and intracellular acidosis (red bar) as well as between control and extracellular acidosis (blue bar; asterisk, p<0.05; one-way ANOVA). <b>B)</b> shows the differences of spike refractory periods between control and intracellular acidosis (red bar) as well as between control and extracellular acidosis (blue bar; one asterisk, p<0.05; one-way ANOVA). <b>C)</b> shows the differences of spike threshold potentials between control and intracellular acidosis (red bar) as well as between control and extracellular acidosis (blue bar; one asterisk, p<0.05; one-way ANOVA).