Histological sections 100 x (A) and 400 x (B) of brains of experimental mice in the absence (Pb-acetate) and existence of AEIA (Pb-acetate + AEIA).

<p>Untreated mice were kept as normal control to compare the structural changes caused by Pb-acetate. Yellow arrows represent normal normal cyto-architecture of brain; dotted arrows represent the Pb-acetate mediated development of vacuolated area of degenerated tissues (yellow) and diffused edema (red). C. The manually selected area of diffused edema relative to the whole area of the photomicrograph (400 x, randomly selected areas). D. The blank staining representing vacuolated area of degenerated tissues relative to the whole area of the photomicrograph (400 x, randomly selected areas). Values are expressed as mean ± SE, (n = 60). ^# Values differ significantly from normal control (p < 0.01). ** Values significantly differed from Pb-acetate control (p < 0.01).