Light-emitting diode generated red light (LED-RL) at a fluence of 480 J/cm² significantly decreased relative fibroblast migration speed to 83.0±5.6% (p = 0.0393) compared to matched controls (100±5.8%).

<p><b>A.</b> Pretreatment with 0.0001% resveratrol partially prevented LED-RL’s (480 J/cm²) effects compared to LED-RL alone and resulted in a relative migration speed of 88.1±3.5% (p = 0.4837). Pretreatment with 0.001% resveratrol partially prevented LED-RL’s (480 J/cm²) effects compared to LED-RL alone and resulted in a relative migration speed of 103.7±5.0% (p = 0.0623). Error bars represent standard error of the mean. (* represents P < .05). Fig 3B. Light-emitting diode generated red light (LED-RL) at a fluence of 640 J/cm² significantly decreased relative fibroblast migration speed to 74.4±5.5% (p = 0.0003) compared to matched controls (100±4.2%). Pretreatment with 0.0001% resveratrol partially prevented LED-RL’s (640 J/cm²) effects compared to LED-RL alone and resulted in a relative migration speed of 82.0±4.1% (p = 0.3068). Pretreatment with 0.001% resveratrol significantly prevented LED-RL’s (640 J/cm²) effects compared to LED-RL alone and resulted in a relative migration speed of 99.0±5.3% (p = 0.0009). Error bars represent standard error of the mean. (* represents P < .05). Fig 3C. Light-emitting diode generated red light (LED-RL) at a fluence of 800 J/cm² significantly decreased relative fibroblast migration speed to 68.6±4.5% (p = 0.0003) compared to matched controls (100±4.2%). Pretreatment with 0.0001% resveratrol significantly prevented LED-RL’s (800 J/cm²) effects compared to LED-RL alone and resulted in a relative migration speed of 83.0±3.9% (p = 0.019). Pretreatment with 0.001% resveratrol significantly prevented LED-RL’s (800 J/cm²) effects compared to LED-RL alone and resulted in a relative migration speed of 101.9±4.2% (p = 0.0006). Error bars represent standard error of the mean. (* represents P < .05).