<p>TIM-3 co-immunoprecipitation analysis of unactivated and 15 min. stimulation with anti-CD3/CD28 beads (activated). Equivalent amounts of protein (~2mg) were co-immunoprecipitated with pAb anti-TIM-3 antibody and western blot was performed using capillary electrophoresis. Cleared lysate served as a loading control for individual antibody reactivity.</p
<p>(A) CD8<sup><b>+</b></sup> T cells from donors (n = 12) were stained with antibodies against CD44...
International audienceDeciphering how T-cell antigen receptor signals are modulated by coinhibitors ...
Within the solid tumour microenvironment (TME), immunosuppressive mechanisms limit the cytotoxic pot...
<p>(A and B). Human naïve T cells were purified from PBMCs of health donors. Cells were then stimula...
<p>CD4 T cells were stimulated with plate-bound antibodies to CD3 and CD28 immobilized at the indica...
<p>(A and B) Quantification of flow cytometric analysis of cytokine production by different subsets ...
<div><p>TIM-3 (T cell immunoglobulin and mucin-domain containing protein 3) is a member of the TIM f...
<p>A) The kinetic presentation of Tim-3 on the surface of M/M<sub>Ø</sub> following TLR stimulation ...
T cell immunoglobulin mucin-3 (TIM-3) is an immune modulatory molecule that functions in both adapti...
The T cell Immunoglobulin Domain and Mucin Domain 3 (TIM-3) is a type I glycoprotein expressed prima...
T cell immunoglobulin and mucin protein 3 (TIM-3) is a type I cell surface protein that was original...
<p>(A) Flow cytometric analysis demonstrating the relative cell surface expression of chimeric prote...
Although T-cell immunoglobulin mucin 3 (TIM-3) does not contain inhibitory or death signaling motifs...
<p>A) Detection of Tim-3/Gal-9 physical association in un-stimulated and TLR-stimulated M/M<sub>Ø</s...
<div><p>T cell immunoglobulin and mucin protein 3 (TIM-3) is a type I cell surface protein that was ...
<p>(A) CD8<sup><b>+</b></sup> T cells from donors (n = 12) were stained with antibodies against CD44...
International audienceDeciphering how T-cell antigen receptor signals are modulated by coinhibitors ...
Within the solid tumour microenvironment (TME), immunosuppressive mechanisms limit the cytotoxic pot...
<p>(A and B). Human naïve T cells were purified from PBMCs of health donors. Cells were then stimula...
<p>CD4 T cells were stimulated with plate-bound antibodies to CD3 and CD28 immobilized at the indica...
<p>(A and B) Quantification of flow cytometric analysis of cytokine production by different subsets ...
<div><p>TIM-3 (T cell immunoglobulin and mucin-domain containing protein 3) is a member of the TIM f...
<p>A) The kinetic presentation of Tim-3 on the surface of M/M<sub>Ø</sub> following TLR stimulation ...
T cell immunoglobulin mucin-3 (TIM-3) is an immune modulatory molecule that functions in both adapti...
The T cell Immunoglobulin Domain and Mucin Domain 3 (TIM-3) is a type I glycoprotein expressed prima...
T cell immunoglobulin and mucin protein 3 (TIM-3) is a type I cell surface protein that was original...
<p>(A) Flow cytometric analysis demonstrating the relative cell surface expression of chimeric prote...
Although T-cell immunoglobulin mucin 3 (TIM-3) does not contain inhibitory or death signaling motifs...
<p>A) Detection of Tim-3/Gal-9 physical association in un-stimulated and TLR-stimulated M/M<sub>Ø</s...
<div><p>T cell immunoglobulin and mucin protein 3 (TIM-3) is a type I cell surface protein that was ...
<p>(A) CD8<sup><b>+</b></sup> T cells from donors (n = 12) were stained with antibodies against CD44...
International audienceDeciphering how T-cell antigen receptor signals are modulated by coinhibitors ...
Within the solid tumour microenvironment (TME), immunosuppressive mechanisms limit the cytotoxic pot...