Propofol activates β3γ2L (1:15) and (1:100) receptors with different relative efficacies.

<p>(A) Representative traces of propofol (1–300 μM) direct activation in comparison to 3 mM GABA at β3γ2L (1:15) and (1:100) GABA_ARs. (B) Concentration-response curves of propofol activation at β3γ2L receptors expressed at 1:15 (<i>n</i> = 4) and 1:100 (<i>n</i> = 4) ratios. Data are normalised to the 3 mM GABA response.