Additional file 3: Figure S2. of Epidermal growth factor receptor status and Notch inhibition in non-small cell lung cancer cells

Efstathia Giannopoulou (586695)
Achilleas Nikolakopoulos (3570194)
Dimitra Kotsirilou (3570188)
Angeliki Lampropoulou (3570185)
Sofia Raftopoulou (3570191)
Evangelia Papadimitriou (2452003)
Achilleas Theocharis (3570203)
Thomas Makatsoris (387783)
Konstantinos Fasseas (3570200)
Haralabos Kalofonos (3570197)

Publication date

October 2015

DOI

10.6084/m9.figshare.c.3641495_d2.v1

Abstract

Representative plots for cell cycle analysis in H23, A549, H661 and HCC827 cells as described in âMaterials and Methodsâ section. Control: untreated cells, DAPT: cells treated with DAPT. The G0/G1, S and G2/M phases are indicated with blue, red and green colour, respectively. (PDF 113Â kb

Extracted data

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Data Protection

Additional file 3: Figure S2. of Epidermal growth factor receptor status and Notch inhibition in non-small cell lung cancer cells

Efstathia Giannopoulou (586695)
Achilleas Nikolakopoulos (3570194)
Dimitra Kotsirilou (3570188)
Angeliki Lampropoulou (3570185)
Sofia Raftopoulou (3570191)
Evangelia Papadimitriou (2452003)
Achilleas Theocharis (3570203)
Thomas Makatsoris (387783)
Konstantinos Fasseas (3570200)
Haralabos Kalofonos (3570197)

Open link

Publication date

October 2015

DOI

10.6084/m9.figshare.c.3641495_d2.v1

Abstract

Extracted data

Janet Martin (3022770)
Sohel Julovi (4333738)
Mike Lin (4333741)
Hasanthi de Silva (4333744)
Frances Boyle (505085)
Robert Baxter (102239)

August 2017

Immunohistochemical analysis of nuclear IGFBP-3 in HCC1806 tumors from control, gefitinib-treated (G...

Additional file 3: of Determinant roles of dendritic cell-expressed Notch Delta-like and Jagged ligands on anti-tumor T cell immunity

Elena Tchekneva (6548228)
Mounika Goruganthu (6548231)
Roman Uzhachenko (6548249)
Portia Thomas (6548255)
Anneliese Antonucci (6548258)
Irina Chekneva (6548261)
Michael Koenig (6548264)
Longzhu Piao (6548267)
Anwari Akhter (265269)
Maria Aquino (6158738)
Parvathi Ranganathan (6548270)
Nicholas Long (1728280)
Thomas Magliery (6548273)
Anna Valujskikh (6548276)
Jason Evans (599560)
Rajeswara Arasada (6548279)
Pierre Massion (4913062)
David Carbone (622010)
Anil Shanker (6548282)
Mikhail Dikov (6548285)

April 2019

Figure S3. T-cell expressed PD-1 and NOTCH receptors correlate with DC-expressed NOTCH ligands in hu...

Additional file 2: Figure S1. of Evaluation of epidermal growth factor receptor signaling effects in gastric cancer cell lines by detailed motility-focused phenotypic characterization linked with molecular analysis

Simone Keller (2471176)
Julia Kneissl (4684681)
Verena Grabher-Meier (4684678)
Stefan Heindl (4684687)
Jan Hasenauer (328495)
Dieter Maier (33097)
Julian Mattes (132398)
Peter Winter (196167)
Birgit Luber (4684684)

December 2017

Morphological differences in MKN1 cells after treatment with EGF and/or cetuximab. Denoted are hourl...

Additional file 1: Figure S1. of Distinct effects of EGFR inhibitors on epithelial- and mesenchymal-like esophageal squamous cell carcinoma cells

Masahiro Yoshioka (4320961)
Shinya Ohashi (608381)
Tomomi Ida (4320964)
Yukie Nakai (608383)
Osamu Kikuchi (303987)
Yusuke Amanuma (4320970)
Junichi Matsubara (397152)
Atsushi Yamada (282892)
Shin’ichi Miyamoto (4320973)
Mitsuteru Natsuizaka (681265)
Hiroshi Nakagawa (269927)
Tsutomu Chiba (170849)
Hiroshi Seno (567264)
Manabu Muto (223899)

August 2017

Effects of EGFR inhibition or activation on immortalized-human esophageal epithelial cells. EPC2-hTE...

Additional file 3: Figure S3. of Inhibition of basal-like breast cancer growth by FTY720 in combination with epidermal growth factor receptor kinase blockade

Janet Martin (3022770)
Sohel Julovi (4333738)
Mike Lin (4333741)
Hasanthi de Silva (4333744)
Frances Boyle (505085)
Robert Baxter (102239)

August 2017

CD3 levels in 4T1 tumors grown in wild-type BALB/c mice. Samples were from the experiment shown in F...

Additional file 2: of Hypoxia potentiates gemcitabine-induced stemness in pancreatic cancer cells through AKT/Notch1 signaling

Zhengle Zhang (6020975)
Han Han (174736)
Yuping Rong (6020978)
Kongfan Zhu (6020981)
Zhongchao Zhu (6020984)
Zhigang Tang (3801919)
Chenglong Xiong (3574784)
Jing Tao (334550)

November 2018

Figure S2. AKT/Notch1 inhibition abolishes gemcitabine-induced metastasis. Non-treated (control) and...

Additional file 4: of GSK3Î˛ regulates epithelial-mesenchymal transition and cancer stem cell properties in triple-negative breast cancer

Geraldine Vijay (6437930)
Na Zhao (112953)
Petra Hollander (6437933)
Mike Toneff (6437936)
Robiya Joseph (6437939)
Mika Pietila (6437942)
Joseph Taube (4458358)
Tapasree Sarkar (6437945)
Esmeralda Ramirez-Pena (6437948)
Steven Werden (6437951)
Maryam Shariati (4043501)
Ruli Gao (6437954)
Mary Sobieski (5690516)
Clifford Stephan (6437957)
Nathalie Sphyris (6437960)
Noayuki Miura (6437963)
Peter Davies (95719)
Jeffrey Chang (3945326)
Rama Soundararajan (6437966)
Jeffrey Rosen (3172593)
Sendurai Mani (4043519)

March 2019

Figure S2. The drugs that were selected from the screen were validated using FACS. The MDA MB 231 re...

Additional file 5: Figure S5. of Prolonged pemetrexed pretreatment augments persistence of cisplatin-induced DNA damage and eliminates resistant lung cancer stem-like cells associated with EMT

Colin Tièche (3432647)
Ren-Wang Peng (3432653)
Patrick Dorn (3432656)
Laurène Froment (3432641)
Ralph Schmid (3432650)
Thomas Marti (3432644)

February 2016

Applied strategy to determine cell cycle phases and cell cycle phase-specific H2AX phosphorylation l...

Additional file 3: of GSK3Î˛ regulates epithelial-mesenchymal transition and cancer stem cell properties in triple-negative breast cancer

Geraldine Vijay (6437930)
Na Zhao (112953)
Petra Hollander (6437933)
Mike Toneff (6437936)
Robiya Joseph (6437939)
Mika Pietila (6437942)
Joseph Taube (4458358)
Tapasree Sarkar (6437945)
Esmeralda Ramirez-Pena (6437948)
Steven Werden (6437951)
Maryam Shariati (4043501)
Ruli Gao (6437954)
Mary Sobieski (5690516)
Clifford Stephan (6437957)
Nathalie Sphyris (6437960)
Noayuki Miura (6437963)
Peter Davies (95719)
Jeffrey Chang (3945326)
Rama Soundararajan (6437966)
Jeffrey Rosen (3172593)
Sendurai Mani (4043519)

March 2019

Figure S1. The IC50 of the 3 drugs were calculated for the 3 mesenchymal-like cell lines used in thi...

Additional file 3: of Proliferative potential and resistance to immune checkpoint blockade in lung cancer patients

Sarabjot Pabla (5198024)
Jeffrey Conroy (3479114)
Mary Nesline (5198012)
Sean Glenn (3479126)
Antonios Papanicolau-Sengos (3479120)
Blake Burgher (3479138)
Jacob Hagen (4715985)
Vincent Giamo (5198036)
Jonathan Andreas (663929)
Felicia Lenzo (5198027)
Wang Yirong (6289829)
Grace Dy (6262733)
Edwin Yau (6289832)
Amy Early (6289835)
Hongbin Chen (105131)
Wiam Bshara (318111)
Katherine Madden (5198009)
Keisuke Shirai (5198021)
Konstantin Dragnev (5198048)
Laura Tafe (5198018)
Daniele Marin (6262739)
Jason Zhu (2042095)
Jeff Clarke (6289838)
Matthew Labriola (6262736)
Shannon McCall (320448)
Tian Zhang (525467)
Matthew Zibelman (3398630)
Pooja Ghatalia (800258)
Isabel Araujo-Fernandez (6262745)
Arun Singavi (5322230)
Ben George (64738)
Andrew MacKinnon (3448271)
Jonathan Thompson (6262751)
Rajbir Singh (451210)
Robin Jacob (6262754)
Lynn Dressler (17172)
Mark Steciuk (6289841)
Oliver Binns (6289844)
Deepa Kasuganti (5198042)
Neel Shah (636869)
Marc Ernstoff (3526124)
Kunle Odunsi (122690)
Razelle Kurzrock (160706)
Mark Gardner (2221396)
Lorenzo Galluzzi (82794)
Carl Morrison (60355)

February 2019

Figure S2. Disease control rates for PD-L1 positive (TPS >â1%) and negative tumors combined with c...

Additional file 4: Figure S4. of Distinct effects of EGFR inhibitors on epithelial- and mesenchymal-like esophageal squamous cell carcinoma cells

Masahiro Yoshioka (4320961)
Shinya Ohashi (608381)
Tomomi Ida (4320964)
Yukie Nakai (608383)
Osamu Kikuchi (303987)
Yusuke Amanuma (4320970)
Junichi Matsubara (397152)
Atsushi Yamada (282892)
Shin’ichi Miyamoto (4320973)
Mitsuteru Natsuizaka (681265)
Hiroshi Nakagawa (269927)
Tsutomu Chiba (170849)
Hiroshi Seno (567264)
Manabu Muto (223899)

August 2017

Effects of γ-secretase inhibitors on squamous cell differentiation in epithelial-like esophageal cel...

Additional file 1: of EGFR as a biomarker of smoking status and survival in oropharyngeal squamous cell carcinoma

Shanmugappiriya Sivarajah (6197582)
Morris Kostiuk (3761839)
Cameron Lindsay (3761830)
Lakshmi Puttagunta (636939)
Daniel OâConnell (3761251)
Jeffrey Harris (3478718)
Hadi Seikaly (3761239)
Vincent Biron (3761842)

January 2019

Immunofluorescence staining of EGFR in cell lines, normal tissues and oropharyngeal cancer. A) In ce...

Additional file 5: Figure S5. of Inhibition of basal-like breast cancer growth by FTY720 in combination with epidermal growth factor receptor kinase blockade

Janet Martin (3022770)
Sohel Julovi (4333738)
Mike Lin (4333741)
Hasanthi de Silva (4333744)
Frances Boyle (505085)
Robert Baxter (102239)

August 2017

Immunohistochemical analysis of nuclear IGFBP-3 in HCC1806 tumors from control, gefitinib-treated (G...

Additional file 3: of Determinant roles of dendritic cell-expressed Notch Delta-like and Jagged ligands on anti-tumor T cell immunity

Elena Tchekneva (6548228)
Mounika Goruganthu (6548231)
Roman Uzhachenko (6548249)
Portia Thomas (6548255)
Anneliese Antonucci (6548258)
Irina Chekneva (6548261)
Michael Koenig (6548264)
Longzhu Piao (6548267)
Anwari Akhter (265269)
Maria Aquino (6158738)
Parvathi Ranganathan (6548270)
Nicholas Long (1728280)
Thomas Magliery (6548273)
Anna Valujskikh (6548276)
Jason Evans (599560)
Rajeswara Arasada (6548279)
Pierre Massion (4913062)
David Carbone (622010)
Anil Shanker (6548282)
Mikhail Dikov (6548285)

April 2019

Figure S3. T-cell expressed PD-1 and NOTCH receptors correlate with DC-expressed NOTCH ligands in hu...

Simone Keller (2471176)
Julia Kneissl (4684681)
Verena Grabher-Meier (4684678)
Stefan Heindl (4684687)
Jan Hasenauer (328495)
Dieter Maier (33097)
Julian Mattes (132398)
Peter Winter (196167)
Birgit Luber (4684684)

December 2017

Morphological differences in MKN1 cells after treatment with EGF and/or cetuximab. Denoted are hourl...

Additional file 1: Figure S1. of Distinct effects of EGFR inhibitors on epithelial- and mesenchymal-like esophageal squamous cell carcinoma cells

Masahiro Yoshioka (4320961)
Shinya Ohashi (608381)
Tomomi Ida (4320964)
Yukie Nakai (608383)
Osamu Kikuchi (303987)
Yusuke Amanuma (4320970)
Junichi Matsubara (397152)
Atsushi Yamada (282892)
Shin’ichi Miyamoto (4320973)
Mitsuteru Natsuizaka (681265)
Hiroshi Nakagawa (269927)
Tsutomu Chiba (170849)
Hiroshi Seno (567264)
Manabu Muto (223899)

August 2017

Effects of EGFR inhibition or activation on immortalized-human esophageal epithelial cells. EPC2-hTE...

Additional file 3: Figure S3. of Inhibition of basal-like breast cancer growth by FTY720 in combination with epidermal growth factor receptor kinase blockade

Janet Martin (3022770)
Sohel Julovi (4333738)
Mike Lin (4333741)
Hasanthi de Silva (4333744)
Frances Boyle (505085)
Robert Baxter (102239)

August 2017

CD3 levels in 4T1 tumors grown in wild-type BALB/c mice. Samples were from the experiment shown in F...

Additional file 2: of Hypoxia potentiates gemcitabine-induced stemness in pancreatic cancer cells through AKT/Notch1 signaling

Zhengle Zhang (6020975)
Han Han (174736)
Yuping Rong (6020978)
Kongfan Zhu (6020981)
Zhongchao Zhu (6020984)
Zhigang Tang (3801919)
Chenglong Xiong (3574784)
Jing Tao (334550)

November 2018

Figure S2. AKT/Notch1 inhibition abolishes gemcitabine-induced metastasis. Non-treated (control) and...

Additional file 4: of GSK3Î˛ regulates epithelial-mesenchymal transition and cancer stem cell properties in triple-negative breast cancer

Geraldine Vijay (6437930)
Na Zhao (112953)
Petra Hollander (6437933)
Mike Toneff (6437936)
Robiya Joseph (6437939)
Mika Pietila (6437942)
Joseph Taube (4458358)
Tapasree Sarkar (6437945)
Esmeralda Ramirez-Pena (6437948)
Steven Werden (6437951)
Maryam Shariati (4043501)
Ruli Gao (6437954)
Mary Sobieski (5690516)
Clifford Stephan (6437957)
Nathalie Sphyris (6437960)
Noayuki Miura (6437963)
Peter Davies (95719)
Jeffrey Chang (3945326)
Rama Soundararajan (6437966)
Jeffrey Rosen (3172593)
Sendurai Mani (4043519)

March 2019

Figure S2. The drugs that were selected from the screen were validated using FACS. The MDA MB 231 re...

Additional file 5: Figure S5. of Prolonged pemetrexed pretreatment augments persistence of cisplatin-induced DNA damage and eliminates resistant lung cancer stem-like cells associated with EMT

Colin Tièche (3432647)
Ren-Wang Peng (3432653)
Patrick Dorn (3432656)
Laurène Froment (3432641)
Ralph Schmid (3432650)
Thomas Marti (3432644)

February 2016

Applied strategy to determine cell cycle phases and cell cycle phase-specific H2AX phosphorylation l...

Additional file 3: of GSK3Î˛ regulates epithelial-mesenchymal transition and cancer stem cell properties in triple-negative breast cancer

Geraldine Vijay (6437930)
Na Zhao (112953)
Petra Hollander (6437933)
Mike Toneff (6437936)
Robiya Joseph (6437939)
Mika Pietila (6437942)
Joseph Taube (4458358)
Tapasree Sarkar (6437945)
Esmeralda Ramirez-Pena (6437948)
Steven Werden (6437951)
Maryam Shariati (4043501)
Ruli Gao (6437954)
Mary Sobieski (5690516)
Clifford Stephan (6437957)
Nathalie Sphyris (6437960)
Noayuki Miura (6437963)
Peter Davies (95719)
Jeffrey Chang (3945326)
Rama Soundararajan (6437966)
Jeffrey Rosen (3172593)
Sendurai Mani (4043519)

March 2019

Figure S1. The IC50 of the 3 drugs were calculated for the 3 mesenchymal-like cell lines used in thi...

Additional file 3: of Proliferative potential and resistance to immune checkpoint blockade in lung cancer patients

Sarabjot Pabla (5198024)
Jeffrey Conroy (3479114)
Mary Nesline (5198012)
Sean Glenn (3479126)
Antonios Papanicolau-Sengos (3479120)
Blake Burgher (3479138)
Jacob Hagen (4715985)
Vincent Giamo (5198036)
Jonathan Andreas (663929)
Felicia Lenzo (5198027)
Wang Yirong (6289829)
Grace Dy (6262733)
Edwin Yau (6289832)
Amy Early (6289835)
Hongbin Chen (105131)
Wiam Bshara (318111)
Katherine Madden (5198009)
Keisuke Shirai (5198021)
Konstantin Dragnev (5198048)
Laura Tafe (5198018)
Daniele Marin (6262739)
Jason Zhu (2042095)
Jeff Clarke (6289838)
Matthew Labriola (6262736)
Shannon McCall (320448)
Tian Zhang (525467)
Matthew Zibelman (3398630)
Pooja Ghatalia (800258)
Isabel Araujo-Fernandez (6262745)
Arun Singavi (5322230)
Ben George (64738)
Andrew MacKinnon (3448271)
Jonathan Thompson (6262751)
Rajbir Singh (451210)
Robin Jacob (6262754)
Lynn Dressler (17172)
Mark Steciuk (6289841)
Oliver Binns (6289844)
Deepa Kasuganti (5198042)
Neel Shah (636869)
Marc Ernstoff (3526124)
Kunle Odunsi (122690)
Razelle Kurzrock (160706)
Mark Gardner (2221396)
Lorenzo Galluzzi (82794)
Carl Morrison (60355)

February 2019

Figure S2. Disease control rates for PD-L1 positive (TPS >â1%) and negative tumors combined with c...

Additional file 4: Figure S4. of Distinct effects of EGFR inhibitors on epithelial- and mesenchymal-like esophageal squamous cell carcinoma cells

Masahiro Yoshioka (4320961)
Shinya Ohashi (608381)
Tomomi Ida (4320964)
Yukie Nakai (608383)
Osamu Kikuchi (303987)
Yusuke Amanuma (4320970)
Junichi Matsubara (397152)
Atsushi Yamada (282892)
Shin’ichi Miyamoto (4320973)
Mitsuteru Natsuizaka (681265)
Hiroshi Nakagawa (269927)
Tsutomu Chiba (170849)
Hiroshi Seno (567264)
Manabu Muto (223899)

August 2017

Effects of γ-secretase inhibitors on squamous cell differentiation in epithelial-like esophageal cel...

Additional file 1: of EGFR as a biomarker of smoking status and survival in oropharyngeal squamous cell carcinoma

Shanmugappiriya Sivarajah (6197582)
Morris Kostiuk (3761839)
Cameron Lindsay (3761830)
Lakshmi Puttagunta (636939)
Daniel OâConnell (3761251)
Jeffrey Harris (3478718)
Hadi Seikaly (3761239)
Vincent Biron (3761842)

January 2019

Immunofluorescence staining of EGFR in cell lines, normal tissues and oropharyngeal cancer. A) In ce...

Additional file 5: Figure S5. of Inhibition of basal-like breast cancer growth by FTY720 in combination with epidermal growth factor receptor kinase blockade

Janet Martin (3022770)
Sohel Julovi (4333738)
Mike Lin (4333741)
Hasanthi de Silva (4333744)
Frances Boyle (505085)
Robert Baxter (102239)

August 2017

Immunohistochemical analysis of nuclear IGFBP-3 in HCC1806 tumors from control, gefitinib-treated (G...

Additional file 3: of Determinant roles of dendritic cell-expressed Notch Delta-like and Jagged ligands on anti-tumor T cell immunity

Elena Tchekneva (6548228)
Mounika Goruganthu (6548231)
Roman Uzhachenko (6548249)
Portia Thomas (6548255)
Anneliese Antonucci (6548258)
Irina Chekneva (6548261)
Michael Koenig (6548264)
Longzhu Piao (6548267)
Anwari Akhter (265269)
Maria Aquino (6158738)
Parvathi Ranganathan (6548270)
Nicholas Long (1728280)
Thomas Magliery (6548273)
Anna Valujskikh (6548276)
Jason Evans (599560)
Rajeswara Arasada (6548279)
Pierre Massion (4913062)
David Carbone (622010)
Anil Shanker (6548282)
Mikhail Dikov (6548285)

April 2019

Figure S3. T-cell expressed PD-1 and NOTCH receptors correlate with DC-expressed NOTCH ligands in hu...

Additional file 3: Figure S2. of Epidermal growth factor receptor status and Notch inhibition in non-small cell lung cancer cells

Abstract

Extracted data

Additional file 3: Figure S2. of Epidermal growth factor receptor status and Notch inhibition in non-small cell lung cancer cells

Abstract

Extracted data

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