<p>(a) Neuropathology scores were measured in infected (n = 5), control (n = 6), infected and IL-10 treated (n = 5) and IL-10 treated controls (n = 6). Data are mean ±SE. *:p<0.05 Tukey post-hoc test (b) CNS parasitosis in IL-10 treated (n = 6) and untreated infected mice (n = 6) was measured by Q-PCR. Boxes are median and IQR, whiskers 10<sup>th</sup> and 90<sup>th</sup> percentile. *:P<0.05 Unpaired <i>t-</i>test with Welch correction.</p
In many infectious diseases, the immune response operates as a double-edged sword. While required fo...
In experimental murine trypanosomiasis, resistance is often scored as the capacity to control peak p...
BACKGROUND: To date, no biological marker for treatment outcome in human African trypanosomiasis (HA...
Invasion of the central nervous system (CNS) by African trypanosomes represents a critical step in t...
<div><p>Invasion of the central nervous system (CNS) by African trypanosomes represents a critical s...
The relationship of neuropathology to CNS inflammatory and counter-inflammatory cytokine production ...
Funding: The study was funded by the Wellcome Trust grants 082786 and 094691 (www.wellcome.ac.uk). T...
Human African trypanosomiasis (HAT) is caused by infection due to protozoan parasites of the Trypano...
<div><p>Background</p><p>Sleeping sickness due to <i>Trypanosoma brucei rhodesiense</i> has a wide s...
The late, or encephalitic, stage of human African trypanosomiasis (HAT), or sleeping sickness, is ty...
<p>(a) Plasma IFN-γ and (b) Plasma TNF-α concentrations in infected (n = 17), control (n = 8), infec...
In this study, we examined the effects of interleukin-10 (IL-10) on the outcome of experimental cere...
Background Sleeping sickness due to Trypanosoma brucei rhodesiense has a wide spectrum of clinical p...
Human African trypanosomiasis progresses from an early (hemolymphatic) stage, through CNS invasion t...
Resistance to Trypanosoma brucei brucei has been correlated with the ability of infected animals to ...
In many infectious diseases, the immune response operates as a double-edged sword. While required fo...
In experimental murine trypanosomiasis, resistance is often scored as the capacity to control peak p...
BACKGROUND: To date, no biological marker for treatment outcome in human African trypanosomiasis (HA...
Invasion of the central nervous system (CNS) by African trypanosomes represents a critical step in t...
<div><p>Invasion of the central nervous system (CNS) by African trypanosomes represents a critical s...
The relationship of neuropathology to CNS inflammatory and counter-inflammatory cytokine production ...
Funding: The study was funded by the Wellcome Trust grants 082786 and 094691 (www.wellcome.ac.uk). T...
Human African trypanosomiasis (HAT) is caused by infection due to protozoan parasites of the Trypano...
<div><p>Background</p><p>Sleeping sickness due to <i>Trypanosoma brucei rhodesiense</i> has a wide s...
The late, or encephalitic, stage of human African trypanosomiasis (HAT), or sleeping sickness, is ty...
<p>(a) Plasma IFN-γ and (b) Plasma TNF-α concentrations in infected (n = 17), control (n = 8), infec...
In this study, we examined the effects of interleukin-10 (IL-10) on the outcome of experimental cere...
Background Sleeping sickness due to Trypanosoma brucei rhodesiense has a wide spectrum of clinical p...
Human African trypanosomiasis progresses from an early (hemolymphatic) stage, through CNS invasion t...
Resistance to Trypanosoma brucei brucei has been correlated with the ability of infected animals to ...
In many infectious diseases, the immune response operates as a double-edged sword. While required fo...
In experimental murine trypanosomiasis, resistance is often scored as the capacity to control peak p...
BACKGROUND: To date, no biological marker for treatment outcome in human African trypanosomiasis (HA...