Example of MyoD (red, arrow) and Myogenin (green, arrow) immunofluorescent stainings. These markers could hardly be detected in Pompe muscle and the figure shows an example of a skeletal muscle biopsy from a DMD patient as positive control. Nuclei were stained with Hoechst (blue). (PDF 428Â kb
Figure S1. Reduced fiber diameter in GAAKO animals. A. Fiber diameter frequency distribution plot of...
Late-onset Pompe disease is characterized by progressive weakness involving proximal limb and respir...
Figure S2. Pax7-positive cells in Mstn +/+ and Mstn +/â GRMD/GRippet and GRMD-carrier dogs. Lamini...
Examples of muscle fibers that show evidence of recent muscle regeneration. The arrows point to cent...
Unchanged satellite cell proliferation in Pompe disease. Cryosections from Pompe muscle biopsies wer...
Examples of immunofluorescent Ki67 stainings. Left: Human tonsil was stained as positive control and...
Figure S6. Detection of proliferating satellite cells in GAA-deficient limb muscle. Representative i...
Figure S5. Satellite cell numbers are increased in Gaa−/−(Bl6) muscle. A. Satellite cells were detec...
Figure S2. Modest muscle regeneration in Gaa−/−(Bl6) animals. A.eMyHC staining of QF sections from W...
Figure S3. Satellite cell numbers are increased in Gaa−/− TA muscle. The number of Pax7-positive cel...
Figure S4. Identification of Pax7-positive satellite cells by flow cytometry. A. Representative dot ...
Figure S9. Efficient regeneration of GAAKO-muscle after cardiotoxin-induced injury in GAA-deficient ...
<p>(A) Tissue samples, obtained before ERT at age 10 days, processed in paraffin and stained with he...
of robust satellite cell activation and muscle regeneration during the progression of Pompe disease ...
Antibody validation for Pax7, MyoD, and MyoG in growth and differentiation media. Representative ima...
Figure S1. Reduced fiber diameter in GAAKO animals. A. Fiber diameter frequency distribution plot of...
Late-onset Pompe disease is characterized by progressive weakness involving proximal limb and respir...
Figure S2. Pax7-positive cells in Mstn +/+ and Mstn +/â GRMD/GRippet and GRMD-carrier dogs. Lamini...
Examples of muscle fibers that show evidence of recent muscle regeneration. The arrows point to cent...
Unchanged satellite cell proliferation in Pompe disease. Cryosections from Pompe muscle biopsies wer...
Examples of immunofluorescent Ki67 stainings. Left: Human tonsil was stained as positive control and...
Figure S6. Detection of proliferating satellite cells in GAA-deficient limb muscle. Representative i...
Figure S5. Satellite cell numbers are increased in Gaa−/−(Bl6) muscle. A. Satellite cells were detec...
Figure S2. Modest muscle regeneration in Gaa−/−(Bl6) animals. A.eMyHC staining of QF sections from W...
Figure S3. Satellite cell numbers are increased in Gaa−/− TA muscle. The number of Pax7-positive cel...
Figure S4. Identification of Pax7-positive satellite cells by flow cytometry. A. Representative dot ...
Figure S9. Efficient regeneration of GAAKO-muscle after cardiotoxin-induced injury in GAA-deficient ...
<p>(A) Tissue samples, obtained before ERT at age 10 days, processed in paraffin and stained with he...
of robust satellite cell activation and muscle regeneration during the progression of Pompe disease ...
Antibody validation for Pax7, MyoD, and MyoG in growth and differentiation media. Representative ima...
Figure S1. Reduced fiber diameter in GAAKO animals. A. Fiber diameter frequency distribution plot of...
Late-onset Pompe disease is characterized by progressive weakness involving proximal limb and respir...
Figure S2. Pax7-positive cells in Mstn +/+ and Mstn +/â GRMD/GRippet and GRMD-carrier dogs. Lamini...