Relating Cortical Atrophy in Temporal Lobe Epilepsy with Graph Diffusion-Based Network Models - Fig 1

<p>(a) TLE-MTS atrophy distribution. As expected, the hippocampus has the highest atrophy, consistent with TLE-MTS. (b) Pearson correlation <i>R</i> between Φ₁ and measured atrophy vs. the number of eigen-modes used. Peak <i>R</i> is reached when eigen-modes <b>u</b>_2–68 are used. (c) Atrophy distribution estimated using Model 1 using eigen-modes <b>u</b>₂ − <b>u</b>₆₈. Model 2: (d) Correlation <i>R</i> obtained when each node is seeded (model Φ₂). The highest <i>R</i> is obtained when the hippocampus is seeded. (e) <i>R</i> vs. graph diffusion depth. Hippocampus seeding leads to the highest <i>R</i> is obtained at <i>t</i> = 5.56, followed by amygdala and the hypothalamus. (f) Estimated TLE-MTS atrophy obtained from Model 2 when the hippocampus is seeded.