<p>For each folding stage, a representative snapshot is shown, with MBP (and its partial folds) in pale red and TF in cyan. The schematic shows a series of events in the cycle, which starts with the interactions between folding intermediates of substrate proteins (MBP in this case) with TF and results in the fully folded substrate protein released from the TF at the end. This may involve more than one TF molecules.</p
Mathematical models for the protein folding-unfolding process involving multiple intermediates have ...
In this study, we apply a hybrid-resolution model, namely, PACE, to characterize the free energy sur...
License, which permits unrestricted use, distribution, and reproduction in any medium, provided the ...
<p>All possible geometries are observed theoretically, however, the route indicated by the grey shad...
<p><b>A.</b> Trigger factor (TF, PDB code: 1W26). The surface of the protein is shown as transparent...
AbstractThe B1 domain of protein G has been a classic model system of folding for decades, the subje...
<p>Snapshots from a typical de novo folding simulation of SFVP in the presence of the ribosome (grey...
<p>(A) Cartoon representation of a crystallographic asymmetric unit containing two copies of the MBP...
Maltose binding protein (MBP) is widely used as a model for protein folding and export studies. We s...
Maltose binding protein (MBP) is widely used as a model for protein folding and export studies. We s...
AbstractA unified and coherent picture for the mechanism of protein folding is emerging. The crucial...
To test whether our recently developed residue-specific force field RSFF2 can reproduce the mutation...
<p><b>A.</b> Contact probabilities of TF residues with MBP (top panel) and P2 (bottom panel). The ba...
We demonstrate that the sub-millisecond protein folding process referred to as "collapse" actually c...
The folding pathway of human FKBP12, a 12 kDa FK506-binding protein (immunophilin), has been charact...
Mathematical models for the protein folding-unfolding process involving multiple intermediates have ...
In this study, we apply a hybrid-resolution model, namely, PACE, to characterize the free energy sur...
License, which permits unrestricted use, distribution, and reproduction in any medium, provided the ...
<p>All possible geometries are observed theoretically, however, the route indicated by the grey shad...
<p><b>A.</b> Trigger factor (TF, PDB code: 1W26). The surface of the protein is shown as transparent...
AbstractThe B1 domain of protein G has been a classic model system of folding for decades, the subje...
<p>Snapshots from a typical de novo folding simulation of SFVP in the presence of the ribosome (grey...
<p>(A) Cartoon representation of a crystallographic asymmetric unit containing two copies of the MBP...
Maltose binding protein (MBP) is widely used as a model for protein folding and export studies. We s...
Maltose binding protein (MBP) is widely used as a model for protein folding and export studies. We s...
AbstractA unified and coherent picture for the mechanism of protein folding is emerging. The crucial...
To test whether our recently developed residue-specific force field RSFF2 can reproduce the mutation...
<p><b>A.</b> Contact probabilities of TF residues with MBP (top panel) and P2 (bottom panel). The ba...
We demonstrate that the sub-millisecond protein folding process referred to as "collapse" actually c...
The folding pathway of human FKBP12, a 12 kDa FK506-binding protein (immunophilin), has been charact...
Mathematical models for the protein folding-unfolding process involving multiple intermediates have ...
In this study, we apply a hybrid-resolution model, namely, PACE, to characterize the free energy sur...
License, which permits unrestricted use, distribution, and reproduction in any medium, provided the ...