Inhibition of T^T repair by β-PV E6. HT1080 cells expressing E6 genes of β-PV types 5, 8 and 20 were irradiated with UVB and levels of T∧T were assayed using In-Cell Western analysis (n = 4 in duplicate, HPV5,****, p < 0.0001; HPV8, ****, p < 0.0001; HPV20, ***, p = 0.0002). Data are presented as mean ± SEM. (PPT 151 kb
Sunlight is the main aetiological agent in the development of non melanoma skin cancer (NMSC), the m...
Toxicity of NU7441, KU-0060648 and Scr7 on the cell lines used in this study. A The 293/TLR line was...
Figure S1. Reduced expression of Zc3h8 in a second cell line and using a second targeting shRNA lead...
textabstractBackground: The failure to mount an effective DNA damage response to repair UV induced c...
Recent work has explored a putative role for the E6 protein from some β-human papilloma-virus genus ...
Table S1. Genes that are differentially expressed by stratified human keratinocytes from different a...
Figure S2. Reproducibility for eWGS for internal control HBB. Data shown is mean ± SD of 4 replicate...
Human papillomaviruses (HPV) are small double-stranded DNA viruses that predominantly form hyperprol...
Changes in the expression of different cellular proteins from the TAN skin in the UVB treated mice. ...
Partial sequencing results for TP53. The LU-HNSSC-26 is homozygous for the single nucleotide polymor...
Doctor of PhilosophyDepartment of BiologyNicholas WallaceBeta genus human papillomaviruses (β-HPV) a...
The p130mE7 mutant is unable to bind 16E7 and HPV48 E7 binds to p21. (A) Nuclear extracts were prepa...
Figure S2. HPV-16 E6 and E7 expression affect p53 and pRb expression. (PDF 116 kb
<p>Persistent genus β-HPV (human papillomavirus) infection is a major co-factor for non-melanoma ski...
Figure S4. Effect of IL-32γ on cell proliferation. HaCaT, A431 and SK-Mel-28 cells were seeded on 96...
Sunlight is the main aetiological agent in the development of non melanoma skin cancer (NMSC), the m...
Toxicity of NU7441, KU-0060648 and Scr7 on the cell lines used in this study. A The 293/TLR line was...
Figure S1. Reduced expression of Zc3h8 in a second cell line and using a second targeting shRNA lead...
textabstractBackground: The failure to mount an effective DNA damage response to repair UV induced c...
Recent work has explored a putative role for the E6 protein from some β-human papilloma-virus genus ...
Table S1. Genes that are differentially expressed by stratified human keratinocytes from different a...
Figure S2. Reproducibility for eWGS for internal control HBB. Data shown is mean ± SD of 4 replicate...
Human papillomaviruses (HPV) are small double-stranded DNA viruses that predominantly form hyperprol...
Changes in the expression of different cellular proteins from the TAN skin in the UVB treated mice. ...
Partial sequencing results for TP53. The LU-HNSSC-26 is homozygous for the single nucleotide polymor...
Doctor of PhilosophyDepartment of BiologyNicholas WallaceBeta genus human papillomaviruses (β-HPV) a...
The p130mE7 mutant is unable to bind 16E7 and HPV48 E7 binds to p21. (A) Nuclear extracts were prepa...
Figure S2. HPV-16 E6 and E7 expression affect p53 and pRb expression. (PDF 116 kb
<p>Persistent genus β-HPV (human papillomavirus) infection is a major co-factor for non-melanoma ski...
Figure S4. Effect of IL-32γ on cell proliferation. HaCaT, A431 and SK-Mel-28 cells were seeded on 96...
Sunlight is the main aetiological agent in the development of non melanoma skin cancer (NMSC), the m...
Toxicity of NU7441, KU-0060648 and Scr7 on the cell lines used in this study. A The 293/TLR line was...
Figure S1. Reduced expression of Zc3h8 in a second cell line and using a second targeting shRNA lead...