Effect of meloxicam and ibuprofen on AQP2 abundance in inner medullary tip and base.

<p>Shown are representative Western blots (left hand panels) from IM tips or bases from rats after 14 days treatment with or without meloxicam (top) or ibuprofen (bottom) probed for total AQP2 (arrows) The top bracket shows 35–50 kDa glycosylated forms; the bottom arrow designates the 29 kDa unglycosylated AQP2. L.C. = loading control. The right hand panels provide combined densitometry from n = 12 rats per group. Bars = Mean ± SEM; *P<0.05 compared with control rats.