Multiple amino acid alignment of TATA-box binding protein 1 from <i>T</i>. <i>solium</i> (TsTBP1).

<p>TsTBP1 was aligned with <i>Sus scrofa</i> TBP1 (SsTBP1, GeneBank ID: XP_003361466.1), <i>Homo sapiens</i> TBP1 (HsTBP1, GeneBank ID: NP_003185.1), <i>E</i>. <i>granulosus</i> TBP1 (EgTBP1, GeneBank ID: CDS17003.1), <i>E</i>. <i>multilocularis</i> TBP1 (EmTBP1, GeneBank ID: CDJ04746.1). The NH₂-ter is enclosed in a box, and the remaining amino acid sequence corresponds to the COOH-terminal domain (COOH-ter). Identical amino acids are highlighted in gray background. Important residues that bind TATA-box are in red letters; transcription factor II A (TFIIA) in white; transcription factor II B (TFIIB) in blue; negative cofactor 2 (NC2) in orange and TBP1-associated factor 1 (TAF1) in yellow. Amino acid sequences used to produce the TsTBP probe and the synthetic peptides pTsTBP1-N and pTsTBP1-C are in small boxes and underlined, respectively. Letter X on <i>S</i>. <i>scrofa</i> TBP1 sequence means amino acids not identified. The symbols under the amino acids indicate: (-) absence and (:) homology of amino acids.