A, Rate of MDA-MB231 tumor xenografts growth in mice treated by vehicle control, cisplatin, EGCG and cisplatin/EGCG combination.

<p>Asterisk (*) denotes statistical significance of data obtained from mice treated with EGCG (Day 14, P = o.046), cisplatin (Day 14, p = 0.036) and combinational treatment (Day 6, p = 0.048; Day 11, p = 0.014; Day 12, p = 0.019 and Day 14, p = 0.016) compared to vehicle control treated mice. Error bars represent SEM of multiple tumors. <b>B, <i>Ex-vivo</i> analysis of MDA-MB231 tumor xenografts</b>. H&E staining, top row, TUNEL staining for apoptotic cells, bottom row. Arrows represent nuclear TUNEL staining.