<p>Pep-08 was able to induce T-cell proliferation in 6/9 of total samples while Pep-07 was only able to induce T cell growth in only 3/9 total samples tested.</p
Ag recognition via the TCR is necessary for the expansion of specific T cells that then contribute t...
<p>Antibodies against MHC I and MHC II (A) and anti-CD4 and anti-CD8 (B) were used to block prolifer...
<p>Peripheral blood mononuclear cells (PBMC) obtained from donors 21 (A), 25 (B), 29 (C) 23 (D), 35 ...
<p>A. Splenocytes from a total of 5 mice immunized with polytope construct three times with one week...
There have been reports of immune responses against Cas9 which may impair clinical use. Here the aut...
<p>CFSE-labeled PBMCs of 20 donors were stimulated with 10 µg/ml of peptide in the presence of IL-7,...
Peptide pools are routinely used to study antigen specific T cell responses, both in epitope discove...
<p>(a) Flow cytometry results. The control was normal spleen lymphocytes. The N<sub>71–78</sub> grou...
T cell activation is predicated on the interaction between the T cell receptor and peptide-major his...
<p>CFSE-labeled PBMCs were cultured with single peptides from a “positive” peptide cluster for 8 day...
<p>Antigen specificity of PEPP2-specific CTLs was analyzed. (A) IFN-γ secretion by CTLs responding t...
<p>(A) Cell surface loading. HLA-DR4 expressing dendritic cells (DC) generated from the bone marrow ...
Proliferation of antigen-specific CD4/CD8 T-cells, in response to stimulation using peptide pools, h...
<p>A: CD4+ T-cells were isolated from spleens of mice immunized with single peptides as indicated. T...
SummaryT cell activation is predicated on the interaction between the T cell receptor and peptide-ma...
Ag recognition via the TCR is necessary for the expansion of specific T cells that then contribute t...
<p>Antibodies against MHC I and MHC II (A) and anti-CD4 and anti-CD8 (B) were used to block prolifer...
<p>Peripheral blood mononuclear cells (PBMC) obtained from donors 21 (A), 25 (B), 29 (C) 23 (D), 35 ...
<p>A. Splenocytes from a total of 5 mice immunized with polytope construct three times with one week...
There have been reports of immune responses against Cas9 which may impair clinical use. Here the aut...
<p>CFSE-labeled PBMCs of 20 donors were stimulated with 10 µg/ml of peptide in the presence of IL-7,...
Peptide pools are routinely used to study antigen specific T cell responses, both in epitope discove...
<p>(a) Flow cytometry results. The control was normal spleen lymphocytes. The N<sub>71–78</sub> grou...
T cell activation is predicated on the interaction between the T cell receptor and peptide-major his...
<p>CFSE-labeled PBMCs were cultured with single peptides from a “positive” peptide cluster for 8 day...
<p>Antigen specificity of PEPP2-specific CTLs was analyzed. (A) IFN-γ secretion by CTLs responding t...
<p>(A) Cell surface loading. HLA-DR4 expressing dendritic cells (DC) generated from the bone marrow ...
Proliferation of antigen-specific CD4/CD8 T-cells, in response to stimulation using peptide pools, h...
<p>A: CD4+ T-cells were isolated from spleens of mice immunized with single peptides as indicated. T...
SummaryT cell activation is predicated on the interaction between the T cell receptor and peptide-ma...
Ag recognition via the TCR is necessary for the expansion of specific T cells that then contribute t...
<p>Antibodies against MHC I and MHC II (A) and anti-CD4 and anti-CD8 (B) were used to block prolifer...
<p>Peripheral blood mononuclear cells (PBMC) obtained from donors 21 (A), 25 (B), 29 (C) 23 (D), 35 ...