Access to Polyfunctionalized Chiral Piperidines through Enantioselective Addition–Carbocyclization Cascade Reaction Catalyzed by a Rhodium(I)–Diene Complex

A new addition–carbocyclization cascade reaction initiated by arylboronic acids and catalyzed by a rhodium/chiral diene complex is described. Starting from <i>N</i>-bridged oxoenoate derivatives, highly functionalized piperidines bearing three contiguous stereogenic centers were obtained with excellent enantio- and diastereoselectivities