IN and DNA + IN regimens induce the highest serum IgG and IgA responses after three vaccinations.

<p>Mice were vaccinated three times with the indicated vaccine modalities, serum samples taken 1 week after the last vaccination (week 8) were tested for antigen-specific IgG (a) and IgA (b) by ELISA. Data were analysed using one-way ANOVA with Tukey’s post test, * P <0.05, ** P < 0.01, *** P < 0.001.