<p>(a) Tumor growth factor-β1 (TGF-β1) and Smad signaling was examined by western blot in UUO rat kidneys following treatment with Ang-(1–7). Each column represents the mean ± SEM. *<i>P</i> < 0.05, compared with controls. †<i>P</i> < 0.05, compared with UUO rats. (b) Representative immunohistochemical staining of TGF-β1 expression in UUO rats. Original magnification, 200×.</p
<p>(a and b) Representative RT-PCR results (a) and graphic presentation (b) show α-SMA, E-cadherin a...
TGF-β induces proangiogenic and antiangiogenic factors via parallel but distinct Smad pathways.Backg...
The same protein lysates in Figs 2–4 were used to examine expression of TGF-β1-Smad signaling molecu...
<p><b>A:</b> TGF-β1 expression detected by immunohistochemistry (i ii) and real-time PCR (iii). <b>B...
<p>P8TA/Ang-1 and control (Ang-1/+ or P8TA/+) mice underwent either sham operation or 7 days of UUO ...
<p>(a) TGF-β1 expression in the kidney of mice was evaluated by RT-PCR. (b) The phosphorylated forms...
<p>(A) Double-IF staining of TGF-β and p-Smad3 with CD31 (scale bar = 50 µm). (B) Quantitative analy...
<p>(a) Angiotensin-converting enzyme (ACE), angiotensin II (Ang II), and angiotensin type 1 receptor...
<p>NRK-52E cells were exposed to Ang II (1 μM, 16 h) with or without 1 h pretreatment with Ang-(1–7)...
The present study investigated whether transforming growth factor-beta 1 (TGF-β1) exerts an autocrin...
<p>The different cell types, human tubular epithelial cells (HK-2), murine renal fibroblasts (TFBs) ...
<p>Male Sprague-Dawley rats were subcutaneously implanted with osmotic minipumps to deliver Ang-(1–7...
NRK-49F renal interstitial fibroblasts were incubated with PR-619 (3 μmol/L) for 60 min and then sti...
<p>Western blot (A) and quantitative analysis of renal TGF-β (C), TβR II (D), p-TβR I and TβR I (E) ...
Angiotensin-dependent gene expression in the developing rat kidney. We aimed to identify genes invol...
<p>(a and b) Representative RT-PCR results (a) and graphic presentation (b) show α-SMA, E-cadherin a...
TGF-β induces proangiogenic and antiangiogenic factors via parallel but distinct Smad pathways.Backg...
The same protein lysates in Figs 2–4 were used to examine expression of TGF-β1-Smad signaling molecu...
<p><b>A:</b> TGF-β1 expression detected by immunohistochemistry (i ii) and real-time PCR (iii). <b>B...
<p>P8TA/Ang-1 and control (Ang-1/+ or P8TA/+) mice underwent either sham operation or 7 days of UUO ...
<p>(a) TGF-β1 expression in the kidney of mice was evaluated by RT-PCR. (b) The phosphorylated forms...
<p>(A) Double-IF staining of TGF-β and p-Smad3 with CD31 (scale bar = 50 µm). (B) Quantitative analy...
<p>(a) Angiotensin-converting enzyme (ACE), angiotensin II (Ang II), and angiotensin type 1 receptor...
<p>NRK-52E cells were exposed to Ang II (1 μM, 16 h) with or without 1 h pretreatment with Ang-(1–7)...
The present study investigated whether transforming growth factor-beta 1 (TGF-β1) exerts an autocrin...
<p>The different cell types, human tubular epithelial cells (HK-2), murine renal fibroblasts (TFBs) ...
<p>Male Sprague-Dawley rats were subcutaneously implanted with osmotic minipumps to deliver Ang-(1–7...
NRK-49F renal interstitial fibroblasts were incubated with PR-619 (3 μmol/L) for 60 min and then sti...
<p>Western blot (A) and quantitative analysis of renal TGF-β (C), TβR II (D), p-TβR I and TβR I (E) ...
Angiotensin-dependent gene expression in the developing rat kidney. We aimed to identify genes invol...
<p>(a and b) Representative RT-PCR results (a) and graphic presentation (b) show α-SMA, E-cadherin a...
TGF-β induces proangiogenic and antiangiogenic factors via parallel but distinct Smad pathways.Backg...
The same protein lysates in Figs 2–4 were used to examine expression of TGF-β1-Smad signaling molecu...